SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 PHE A 238
PRO A 235
GLN A  79
ALA A  86
SER A  85
 None
 1.42A 1fm4A-3qslA:
undetectable		 1fm4A-3qslA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 HIS A  95
SER A 148
PRO A 116
THR A 150
VAL A 153
 CIT  A 347 (-4.1A)
CIT  A 347 (-3.6A)
None
CIT  A 347 (-3.2A)
None
 1.43A 2fj1A-3qslA:
undetectable		 2fj1A-3qslA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A  37
PHE A 109
ALA A 252
PHE A  59
LEU A  50
 None
 1.17A 2qb4A-3qslA:
undetectable		 2qb4A-3qslA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ILE A  37
PHE A 109
ALA A 252
PHE A  59
LEU A  50
 None
 1.12A 2qjuA-3qslA:
undetectable		 2qjuA-3qslA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 HIS A  95
SER A 148
PRO A 116
THR A 150
VAL A 153
 CIT  A 347 (-4.1A)
CIT  A 347 (-3.6A)
None
CIT  A 347 (-3.2A)
None
 1.43A 2tctA-3qslA:
undetectable		 2tctA-3qslA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 210
TYR A  47
ALA A 110
ALA A 108
THR A  96
 None
CIT  A 347 (-4.4A)
None
None
None
 1.26A 2x2nD-3qslA:
undetectable		 2x2nD-3qslA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 VAL A 153
PRO A 133
ILE A 141
VAL A 120
VAL A 211
 None
 1.25A 3iw1A-3qslA:
undetectable		 3iw1A-3qslA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 GLY A 305
THR A 308
ASN A 226
 None
 0.53A 3v4tD-3qslA:
undetectable		 3v4tD-3qslA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 9 GLY A  40
GLY A  41
SER A 148
GLY A  74
TYR A  46
 CIT  A 347 (-3.8A)
None
CIT  A 347 (-3.6A)
CIT  A 347 (-3.2A)
CIT  A 347 (-3.3A)
 1.11A 3ztvA-3qslA:
undetectable		 3ztvA-3qslA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ILE A  68
ASP A  70
GLY A  41
SER A 296
GLY A 230
 None
 0.88A 4ac9B-3qslA:
undetectable
4ac9C-3qslA:
undetectable		 4ac9B-3qslA:
21.80
4ac9C-3qslA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 ILE A  52
PRO A  49
GLY A 299
GLN A 247
 None
 0.97A 4g0uB-3qslA:
undetectable		 4g0uB-3qslA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		6 / 12 THR A 194
GLY A  91
GLY A  40
GLY A  41
LEU A  78
ALA A  92
 CIT  A 347 ( 4.3A)
CIT  A 347 (-3.4A)
CIT  A 347 (-3.8A)
None
None
CIT  A 347 (-3.6A)
 1.25A 4uciA-3qslA:
undetectable		 4uciA-3qslA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		6 / 12 THR A 194
GLY A  91
GLY A  40
GLY A  41
LEU A  78
ALA A  92
 CIT  A 347 ( 4.3A)
CIT  A 347 (-3.4A)
CIT  A 347 (-3.8A)
None
None
CIT  A 347 (-3.6A)
 1.24A 4uciB-3qslA:
undetectable		 4uciB-3qslA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 LEU A 249
PHE A  59
ASP A  61
ALA A 248
ILE A  52
 None
 1.38A 4uuuA-3qslA:
undetectable
4uuuB-3qslA:
undetectable		 4uuuA-3qslA:
17.05
4uuuB-3qslA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 HIS A  95
SER A 148
PRO A 116
THR A 150
VAL A 153
 CIT  A 347 (-4.1A)
CIT  A 347 (-3.6A)
None
CIT  A 347 (-3.2A)
None
 1.41A 4v2gB-3qslA:
undetectable		 4v2gB-3qslA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A  47
ILE A 253
PRO A 116
THR A  96
 CIT  A 347 (-4.4A)
None
None
None
 1.22A 4ze1A-3qslA:
undetectable		 4ze1A-3qslA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 145
GLY A 174
GLY A 142
GLY A  74
SER A 148
 None
None
None
CIT  A 347 (-3.2A)
CIT  A 347 (-3.6A)
 0.92A 5gwxA-3qslA:
undetectable		 5gwxA-3qslA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 THR A 150
ALA A  77
GLY A 174
ALA A 175
ASP A  70
 CIT  A 347 (-3.2A)
None
None
None
None
 0.90A 5lf3K-3qslA:
undetectable
5lf3L-3qslA:
undetectable		 5lf3K-3qslA:
20.00
5lf3L-3qslA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qsl PUTATIVE EXPORTED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 THR A 150
ALA A  77
GLY A 174
ALA A 175
ASP A  70
 CIT  A 347 (-3.2A)
None
None
None
None
 0.90A 5lf3Y-3qslA:
undetectable
5lf3Z-3qslA:
undetectable		 5lf3Y-3qslA:
20.00
5lf3Z-3qslA:
21.33