SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qt2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 6 SER A 108
ARG A 205
PRO A 102
GLY A 103
 None
 1.46A 2y7pA-3qt2A:
undetectable		 2y7pA-3qt2A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 PRO A  13
GLU A  58
TYR A  45
 None
 0.64A 2zmbA-3qt2A:
undetectable		 2zmbA-3qt2A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 LEU A 151
TRP A 177
TYR A 153
 None
BGC  A 318 (-3.9A)
None
 1.01A 3aicA-3qt2A:
undetectable		 3aicA-3qt2A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 LEU A 151
TRP A 177
TYR A 153
 None
BGC  A 318 (-3.9A)
None
 0.99A 3aicB-3qt2A:
undetectable		 3aicB-3qt2A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 LEU A 151
TRP A 177
TYR A 153
 None
BGC  A 318 (-3.9A)
None
 0.97A 3aicE-3qt2A:
undetectable		 3aicE-3qt2A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 LEU A 151
TRP A 177
TYR A 153
 None
BGC  A 318 (-3.9A)
None
 1.00A 3aicF-3qt2A:
undetectable		 3aicF-3qt2A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 LEU A 151
TRP A 177
TYR A 153
 None
BGC  A 318 (-3.9A)
None
 0.96A 3aicH-3qt2A:
undetectable		 3aicH-3qt2A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 5 VAL A  78
VAL A  47
THR A  17
THR A  80
 None
 1.28A 3bjwD-3qt2A:
undetectable		 3bjwD-3qt2A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		5 / 12 THR A  68
VAL A  67
PHE A  74
VAL A  78
THR A  59
 None
 1.32A 3elzC-3qt2A:
undetectable		 3elzC-3qt2A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 8 TYR A 152
GLY A  22
ASP A 208
PRO A 206
 BGC  A 316 (-4.2A)
BGC  A 316 ( 4.7A)
None
None
 0.92A 6ag0A-3qt2A:
undetectable		 6ag0A-3qt2A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3qt2 INTERLEUKIN-5
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 6 SER A  77
ALA A  51
ALA A  76
SER A  75
 BGC  A 317 (-3.6A)
None
None
None
 1.05A 6bocA-3qt2A:
undetectable
6bocB-3qt2A:
undetectable
6bocC-3qt2A:
undetectable
6bocD-3qt2A:
undetectable		 6bocA-3qt2A:
4.93
6bocB-3qt2A:
4.93
6bocC-3qt2A:
4.93
6bocD-3qt2A:
4.93