SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qt3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 10 ALA A  85
PHE A  87
GLY A  89
GLU A  82
LEU A   8
 None
 1.31A 1cmcA-3qt3A:
undetectable
1cmcB-3qt3A:
undetectable		 1cmcA-3qt3A:
13.85
1cmcB-3qt3A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 10 GLU A  82
LEU A   8
ALA A  85
PHE A  87
GLY A  89
 None
 1.33A 1cmcA-3qt3A:
undetectable
1cmcB-3qt3A:
undetectable		 1cmcA-3qt3A:
13.85
1cmcB-3qt3A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 12 SER A  68
TYR A 139
HIS A 350
SER A 219
PHE A 408
 None
None
None
None
EDO  A 428 (-4.7A)
 1.35A 1fdsA-3qt3A:
undetectable		 1fdsA-3qt3A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 10 THR A 351
GLY A 394
HIS A 392
ALA A 301
ILE A 359
 None
 1.01A 1likA-3qt3A:
undetectable		 1likA-3qt3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 11 GLU A  82
LEU A   8
ALA A  85
PHE A  87
GLY A  89
 None
 1.30A 1mjqA-3qt3A:
undetectable
1mjqB-3qt3A:
undetectable		 1mjqA-3qt3A:
13.59
1mjqB-3qt3A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 10 GLU A  82
LEU A   8
ALA A  85
PHE A  87
GLY A  89
 None
 1.36A 1mjqC-3qt3A:
undetectable
1mjqD-3qt3A:
undetectable		 1mjqC-3qt3A:
13.59
1mjqD-3qt3A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 10 GLU A  82
LEU A   8
ALA A  85
PHE A  87
GLY A  89
 None
 1.30A 1mjqG-3qt3A:
undetectable
1mjqH-3qt3A:
undetectable		 1mjqG-3qt3A:
13.59
1mjqH-3qt3A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 6 PHE A  32
TYR A  73
GLY A  16
LYS A  17
 None
 1.18A 2i30A-3qt3A:
undetectable		 2i30A-3qt3A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 5 TRP A 172
ALA A 231
LEU A 137
ALA A 235
 None
 1.30A 2jstA-3qt3A:
undetectable
2jstB-3qt3A:
undetectable		 2jstA-3qt3A:
10.30
2jstB-3qt3A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		3 / 3 ASN A 334
ARG A 335
ASP A 221
 None
 0.87A 2qe6B-3qt3A:
undetectable		 2qe6B-3qt3A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		3 / 3 LYS A 315
ARG A 263
VAL A 237
 None
 0.92A 2r2vC-3qt3A:
undetectable
2r2vD-3qt3A:
undetectable		 2r2vC-3qt3A:
5.93
2r2vD-3qt3A:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 11 PHE A  36
ILE A 424
PHE A  32
VAL A  77
LEU A  83
 None
 0.99A 3a9eB-3qt3A:
undetectable		 3a9eB-3qt3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 4 LEU A 361
ALA A 343
VAL A 397
PRO A 400
 None
 1.11A 3gv1B-3qt3A:
undetectable		 3gv1B-3qt3A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 7 ARG A 188
ASP A 195
ASP A 221
PHE A 186
 None
 1.49A 3kivA-3qt3A:
undetectable		 3kivA-3qt3A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 8 LEU A  19
TYR A 420
PHE A  36
TYR A  80
 None
 1.18A 3po7A-3qt3A:
undetectable		 3po7A-3qt3A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 5 HIS A 350
SER A 348
GLU A 393
ASP A 406
 None
 1.26A 3tm4A-3qt3A:
undetectable		 3tm4A-3qt3A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 8 PHE A  36
HIS A  72
GLU A 421
ILE A 424
 None
 1.15A 4cx7A-3qt3A:
undetectable
4cx7B-3qt3A:
undetectable		 4cx7A-3qt3A:
23.25
4cx7B-3qt3A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 6 GLU A 393
ILE A 359
ASN A 302
VAL A  53
 None
None
EDO  A 428 (-3.7A)
None
 0.91A 4ejwB-3qt3A:
undetectable		 4ejwB-3qt3A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 11 PHE A 395
GLY A 347
ALA A 360
GLY A 394
ILE A  23
 None
 1.13A 4kt0A-3qt3A:
undetectable
4kt0J-3qt3A:
undetectable		 4kt0A-3qt3A:
20.16
4kt0J-3qt3A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 11 ILE A 270
ALA A 235
LEU A 312
LEU A 306
ILE A 229
 None
 1.19A 4p66A-3qt3A:
undetectable		 4p66A-3qt3A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		3 / 5 GLY A 215
GLY A 226
GLU A 288
 None
 0.49A 4z2eA-3qt3A:
undetectable
4z2eD-3qt3A:
undetectable		 4z2eA-3qt3A:
22.26
4z2eD-3qt3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 4 VAL A 397
ALA A 342
PHE A 395
THR A 384
 None
 1.45A 4z4fA-3qt3A:
undetectable		 4z4fA-3qt3A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 4 VAL A 397
ALA A 342
PHE A 395
THR A 384
 None
 1.45A 4z4hA-3qt3A:
undetectable		 4z4hA-3qt3A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 8 PHE A  32
ILE A 424
TYR A 420
GLY A  16
 None
 0.86A 5esfA-3qt3A:
undetectable		 5esfA-3qt3A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 7 SER A 308
PRO A 230
PHE A 234
SER A  68
 None
 1.24A 5l1fC-3qt3A:
undetectable		 5l1fC-3qt3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		5 / 10 ALA A 235
VAL A 237
LYS A 315
ILE A 309
VAL A 303
 None
 1.11A 5nukA-3qt3A:
undetectable		 5nukA-3qt3A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 8 ALA A 259
LEU A 255
ALA A 246
GLU A 247
 None
 0.78A 6mdqA-3qt3A:
undetectable		 6mdqA-3qt3A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426
(Clostridium
perfringens) 		4 / 8 GLY A 215
LEU A 202
GLY A 203
LEU A 197
 None
 0.70A 6mdqA-3qt3A:
undetectable		 6mdqA-3qt3A:
11.35