SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qta'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 9 ILE A 169
LEU A 178
VAL A  38
ALA A  36
LEU A  28
 None
 1.01A 1e7bA-3qtaA:
undetectable		 1e7bA-3qtaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 12 PHE A 119
PHE A 189
ILE A 131
ILE A 123
ILE A 193
 None
 1.25A 1r5lA-3qtaA:
undetectable		 1r5lA-3qtaA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		4 / 7 PHE A  79
ALA A  84
ALA A  88
THR A  92
 None
 0.70A 2wx2A-3qtaA:
undetectable		 2wx2A-3qtaA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 12 PHE A  79
ALA A  25
ALA A  84
ALA A  88
THR A  92
 None
 0.69A 2x2nA-3qtaA:
undetectable		 2x2nA-3qtaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 12 PHE A  79
ALA A  37
ALA A  84
ALA A  88
THR A  92
 None
 1.13A 2x2nA-3qtaA:
undetectable		 2x2nA-3qtaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 12 PHE A  79
ALA A  25
ALA A  84
ALA A  88
THR A  92
 None
 0.71A 2x2nB-3qtaA:
undetectable		 2x2nB-3qtaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 12 PHE A  79
ALA A  37
ALA A  84
ALA A  88
THR A  92
 None
 1.12A 2x2nB-3qtaA:
undetectable		 2x2nB-3qtaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 12 PHE A  79
VAL A  24
ALA A  84
ALA A  88
THR A  92
 None
 1.10A 2x2nC-3qtaA:
undetectable		 2x2nC-3qtaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		4 / 8 LEU A 178
SER A 165
VAL A  38
ALA A 175
 None
 0.76A 3ax9A-3qtaA:
undetectable		 3ax9A-3qtaA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 11 LEU A  90
LEU A 115
LEU A  28
VAL A  34
SER A 165
 None
 1.08A 3frbX-3qtaA:
undetectable		 3frbX-3qtaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		4 / 8 PHE A  79
ALA A  84
ALA A  88
THR A  92
 None
 0.54A 3l4dA-3qtaA:
undetectable		 3l4dA-3qtaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		4 / 8 PHE A  79
TYR A  61
ALA A  88
THR A  92
 None
 0.98A 3l4dA-3qtaA:
undetectable		 3l4dA-3qtaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		4 / 8 PHE A  79
ALA A  84
ALA A  88
THR A  92
 None
 0.57A 3l4dD-3qtaA:
undetectable		 3l4dD-3qtaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		4 / 6 GLY A 118
THR A 116
SER A  27
VAL A  24
 None
 1.15A 5ewuB-3qtaA:
undetectable		 5ewuB-3qtaA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 10 ALA A  32
LEU A  28
ALA A 175
THR A  83
LEU A  90
 None
 1.02A 6h1lA-3qtaA:
undetectable		 6h1lA-3qtaA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 10 ALA A  32
VAL A  34
ALA A 175
THR A  83
LEU A  90
 None
 1.18A 6h1lA-3qtaA:
undetectable		 6h1lA-3qtaA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3qta CHEMOTAXIS PROTEIN
CHEC
(Haloarcula
marismortui) 		5 / 11 ALA A  32
LEU A  28
ALA A 175
THR A  83
LEU A  90
 None
 0.97A 6h1lB-3qtaA:
undetectable		 6h1lB-3qtaA:
19.96