SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qtd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 338
SER A 332
ASN A 343
 None
 0.76A 1bx4A-3qtdA:
undetectable		 1bx4A-3qtdA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.07A 1rxcF-3qtdA:
undetectable		 1rxcF-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 257
PHE A 259
ALA A 262
LEU A 275
VAL A 380
 None
 1.15A 1ukbA-3qtdA:
undetectable		 1ukbA-3qtdA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 315
ASP A 308
ASN A 343
 None
 1.05A 2bm9A-3qtdA:
undetectable		 2bm9A-3qtdA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 300
VAL A 424
VAL A 253
ILE A 428
 None
 0.99A 2hyyA-3qtdA:
undetectable		 2hyyA-3qtdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 300
VAL A 424
VAL A 253
ILE A 428
 None
 1.00A 2hyyB-3qtdA:
undetectable		 2hyyB-3qtdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 202
THR A 160
VAL A 191
 None
 0.95A 2q64A-3qtdA:
undetectable		 2q64A-3qtdA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 265
TYR A 269
SER A 332
 None
 0.70A 2xatA-3qtdA:
undetectable		 2xatA-3qtdA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 203
ARG A 232
ARG A 431
 None
 0.93A 3k37A-3qtdA:
undetectable		 3k37A-3qtdA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 300
VAL A 424
VAL A 253
ILE A 428
 None
 1.00A 3k5vA-3qtdA:
undetectable		 3k5vA-3qtdA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 300
VAL A 424
VAL A 253
ILE A 428
 None
 0.99A 3k5vB-3qtdA:
undetectable		 3k5vB-3qtdA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.09A 3kvvA-3qtdA:
undetectable		 3kvvA-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.04A 3kvvB-3qtdA:
undetectable		 3kvvB-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.07A 3kvvC-3qtdA:
undetectable		 3kvvC-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.00A 3kvvD-3qtdA:
undetectable		 3kvvD-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.09A 3kvvE-3qtdA:
undetectable		 3kvvE-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.10A 3kvvF-3qtdA:
undetectable		 3kvvF-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 291
PHE A 256
VAL A 424
ILE A 421
 None
 0.93A 3pglA-3qtdA:
undetectable		 3pglA-3qtdA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.06A 4e1vB-3qtdA:
undetectable		 4e1vB-3qtdA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A   9
GLN A  43
ARG A  61
VAL A  12
 None
 1.06A 4e1vF-3qtdA:
undetectable		 4e1vF-3qtdA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 SER A 438
ALA A 423
VAL A 422
 None
 0.62A 4o2bA-3qtdA:
undetectable		 4o2bA-3qtdA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 430
ASN A 349
ALA A 299
GLY A 301
LEU A 300
 None
 1.26A 4oadA-3qtdA:
undetectable		 4oadA-3qtdA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 213
THR A 184
HIS A 186
 None
 0.44A 4q15A-3qtdA:
undetectable		 4q15A-3qtdA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 213
THR A 184
HIS A 186
 None
 0.42A 4q15B-3qtdA:
undetectable		 4q15B-3qtdA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 213
THR A 184
HIS A 186
 None
 0.44A 4ydqB-3qtdA:
undetectable		 4ydqB-3qtdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  92
ALA A  78
PHE A  65
THR A  80
 None
 1.32A 4z4fA-3qtdA:
2.7		 4z4fA-3qtdA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  92
ALA A  78
PHE A  65
THR A  80
 None
 1.32A 4z4hA-3qtdA:
2.7		 4z4hA-3qtdA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 352
ILE A 290
ALA A 262
ILE A 263
PHE A 284
 None
 1.19A 5d75A-3qtdA:
undetectable		 5d75A-3qtdA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 337
GLY A 333
SER A 332
LEU A 336
TYR A 326
 None
 1.15A 5hwkA-3qtdA:
undetectable		 5hwkA-3qtdA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 337
GLY A 333
SER A 332
LEU A 336
TYR A 326
 None
 1.15A 5hwkB-3qtdA:
undetectable		 5hwkB-3qtdA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 3qtd PMBA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 351
ARG A 430
ASP A 427
GLY A 425
 None
 1.16A 5mraA-3qtdA:
undetectable
5mraB-3qtdA:
undetectable		 5mraA-3qtdA:
16.52
5mraB-3qtdA:
16.52