SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qtn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG B 174
ARG B 181
ARG B  77
 None
 0.82A 1l7fA-3qtnB:
undetectable		 1l7fA-3qtnB:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG B 174
ARG B 181
ARG B  77
 None
 0.77A 1l7hA-3qtnB:
undetectable		 1l7hA-3qtnB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		5 / 12 SER B 250
VAL B 180
TYR B 241
ASN B 203
VAL B 202
 None
 1.47A 1x70A-3qtnB:
undetectable		 1x70A-3qtnB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		5 / 12 SER B 250
VAL B 180
TYR B 241
ASN B 203
VAL B 202
 None
 1.47A 1x70B-3qtnB:
undetectable		 1x70B-3qtnB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		5 / 11 GLY B 246
ILE B 206
ALA B 209
VAL B 257
ILE B 261
 None
 0.89A 2nnhA-3qtnB:
1.5		 2nnhA-3qtnB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU B 301
LEU B 311
LYS B 314
ALA B 315
 None
 1.04A 2wekA-3qtnB:
undetectable		 2wekA-3qtnB:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B  93
HIS B  97
ILE B  96
ASN B 142
 None
 1.38A 4o7gA-3qtnB:
3.0
4o7gB-3qtnB:
3.8		 4o7gA-3qtnB:
22.16
4o7gB-3qtnB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3qtn UNCHARACTERIZED
PROTEIN C4B3.07
(Schizosaccharomy
ces
pombe) 		4 / 7 ALA B  99
ILE B  66
LEU B 112
PHE B 116
 None
 1.13A 4uymB-3qtnB:
0.9		 4uymB-3qtnB:
22.93