SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3quc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 157
LYS A 158
VAL A 138
TYR A 153
LEU A   9
 None
 1.36A 1sv5A-3qucA:
2.1		 1sv5A-3qucA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A   9
TRP A 219
LEU A 107
MET A 131
 None
 1.20A 2oaxA-3qucA:
undetectable		 2oaxA-3qucA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A  53
GLU A 178
ASP A 202
 None
 0.81A 2zulA-3qucA:
3.3		 2zulA-3qucA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 128
MET A 131
PHE A 132
PHE A  10
 None
 1.37A 3af3A-3qucA:
undetectable		 3af3A-3qucA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A  53
GLU A 178
ASP A 202
 None
 0.81A 3dmhA-3qucA:
3.4		 3dmhA-3qucA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 157
LYS A 158
VAL A 138
TYR A 153
LEU A   9
 None
 1.39A 4b3oA-3qucA:
undetectable		 4b3oA-3qucA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A  10
GLU A 171
ALA A 167
ALA A 183
GLY A 184
 None
 1.04A 4oaeA-3qucA:
undetectable		 4oaeA-3qucA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 195
VAL A 199
PRO A 174
SER A  53
GLY A 146
 None
 1.28A 4q15A-3qucA:
undetectable		 4q15A-3qucA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 195
VAL A 199
PRO A 174
SER A  53
GLY A 146
 None
 1.26A 4q15B-3qucA:
undetectable		 4q15B-3qucA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 140
GLY A  51
GLU A 171
ALA A 179
TYR A 153
 None
SO4  A 225 ( 3.8A)
None
None
None
 1.27A 4r29B-3qucA:
undetectable		 4r29B-3qucA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 195
VAL A 199
PRO A 174
SER A  53
GLY A 146
 None
 1.21A 4ydqA-3qucA:
2.1		 4ydqA-3qucA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 195
VAL A 199
PRO A 174
SER A  53
GLY A 146
 None
 1.30A 5xiqA-3qucA:
2.2		 5xiqA-3qucA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		4 / 4 PRO A 194
MET A  92
GLY A  94
VAL A 190
 None
 1.47A 6ak3A-3qucA:
undetectable		 6ak3A-3qucA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU A 171
GLU A 178
ALA A 179
LYS A 147
 None
 1.03A 6an0A-3qucA:
3.6		 6an0A-3qucA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3quc INORGANIC
PYROPHOSPHATASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 184
ALA A 183
VAL A 112
LEU A   9
 None
 0.78A 6dwnB-3qucA:
undetectable		 6dwnB-3qucA:
13.79