SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3quf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 ASN A 334
VAL A 143
ILE A 115
LEU A 121
THR A 138
 None
 1.00A 3bexC-3qufA:
undetectable
3bexD-3qufA:
undetectable		 3bexC-3qufA:
20.43
3bexD-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 10 LEU A 121
THR A 138
ASN A 334
VAL A 143
ILE A 115
 None
 0.99A 3bexC-3qufA:
undetectable
3bexD-3qufA:
undetectable		 3bexC-3qufA:
20.43
3bexD-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 10 ASN A 334
VAL A 143
ILE A 115
LEU A 121
THR A 138
 None
 1.00A 3bexE-3qufA:
undetectable
3bexF-3qufA:
undetectable		 3bexE-3qufA:
20.43
3bexF-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 LEU A 121
THR A 138
ASN A 334
VAL A 143
ILE A 115
 None
 0.99A 3bexE-3qufA:
undetectable
3bexF-3qufA:
undetectable		 3bexE-3qufA:
20.43
3bexF-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 ASN A 334
VAL A 143
ILE A 115
LEU A 121
THR A 138
 None
 1.02A 3bf1A-3qufA:
undetectable
3bf1B-3qufA:
undetectable		 3bf1A-3qufA:
20.43
3bf1B-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 LEU A 121
THR A 138
ASN A 334
VAL A 143
ILE A 115
 None
 1.01A 3bf1A-3qufA:
undetectable
3bf1B-3qufA:
undetectable		 3bf1A-3qufA:
20.43
3bf1B-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 ASN A 334
VAL A 143
ILE A 115
LEU A 121
THR A 138
 None
 1.04A 3bf1C-3qufA:
undetectable
3bf1D-3qufA:
undetectable		 3bf1C-3qufA:
20.43
3bf1D-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 LEU A 121
THR A 138
ASN A 334
VAL A 143
ILE A 115
 None
 0.97A 3bf1C-3qufA:
undetectable
3bf1D-3qufA:
undetectable		 3bf1C-3qufA:
20.43
3bf1D-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 ASN A 334
VAL A 143
ILE A 115
LEU A 121
THR A 138
 None
 1.02A 3bf1E-3qufA:
undetectable
3bf1F-3qufA:
undetectable		 3bf1E-3qufA:
20.43
3bf1F-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 LEU A 121
THR A 138
ASN A 334
VAL A 143
ILE A 115
 None
 1.01A 3bf1E-3qufA:
undetectable
3bf1F-3qufA:
undetectable		 3bf1E-3qufA:
20.43
3bf1F-3qufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		3 / 3 PRO A  92
PHE A  96
ALA A 111
 None
 0.70A 3itaD-3qufA:
undetectable		 3itaD-3qufA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 PHE A 172
PHE A 150
ALA A 291
LEU A 157
 None
 0.95A 3t3sC-3qufA:
undetectable		 3t3sC-3qufA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 LEU A 330
GLY A 311
ALA A 313
PHE A 132
ILE A 115
 None
 1.06A 4hytA-3qufA:
undetectable		 4hytA-3qufA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 LEU A 330
GLY A 311
ALA A 313
PHE A 132
ILE A 115
 None
 1.06A 4hytC-3qufA:
undetectable		 4hytC-3qufA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 10 SER A 319
ALA A 315
ALA A 325
ALA A 326
ILE A  41
 None
 1.04A 4lbgA-3qufA:
undetectable		 4lbgA-3qufA:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		3 / 3 SER A 273
MET A 271
ASP A 365
 None
 0.96A 4mm4B-3qufA:
undetectable		 4mm4B-3qufA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 5 ILE A 247
ARG A 237
ASP A 170
VAL A 270
 None
 1.07A 4nkxC-3qufA:
undetectable		 4nkxC-3qufA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 5 ILE A 247
ARG A 237
ASP A 170
VAL A 270
 None
 1.04A 4nkxD-3qufA:
undetectable		 4nkxD-3qufA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 LEU A 121
THR A 138
ASN A 334
VAL A 143
ILE A 115
 None
 1.04A 4o5fA-3qufA:
undetectable
4o5fB-3qufA:
undetectable		 4o5fA-3qufA:
24.48
4o5fB-3qufA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 ASN A 374
LEU A 339
ALA A 145
GLY A 123
ASP A 125
 None
None
None
SO4  A   3 (-3.5A)
None
 1.32A 4qckA-3qufA:
undetectable		 4qckA-3qufA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 5 GLY A 148
ALA A 149
GLY A 274
PRO A 275
 None
 0.84A 4u9uA-3qufA:
undetectable		 4u9uA-3qufA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 5 GLY A 148
ALA A 149
GLY A 274
PRO A 275
 None
 0.86A 4u9uB-3qufA:
undetectable		 4u9uB-3qufA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 PRO A 382
MET A 388
TRP A 231
TYR A 207
 None
 1.45A 4v2zB-3qufA:
undetectable		 4v2zB-3qufA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 PRO A 382
MET A 388
TRP A 231
TYR A 207
 None
 1.42A 4v30B-3qufA:
undetectable		 4v30B-3qufA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 ASN A 334
VAL A 143
ILE A 115
LEU A 121
THR A 138
 None
 1.04A 5b8hA-3qufA:
undetectable
5b8hB-3qufA:
undetectable		 5b8hA-3qufA:
24.47
5b8hB-3qufA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 PHE A 342
ILE A  52
LEU A 330
GLY A  73
PHE A  43
 None
 1.07A 5byjA-3qufA:
undetectable		 5byjA-3qufA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CAD_A_ACTA402_0
(SM80.1 VICILIN)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 6 PHE A  96
ALA A 313
TYR A  79
ASN A 102
 None
 1.17A 5cadA-3qufA:
0.0		 5cadA-3qufA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 TYR A  79
VAL A  55
LEU A 333
GLY A 338
LEU A  83
 None
 1.17A 5ienA-3qufA:
undetectable		 5ienA-3qufA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 GLU A 262
PHE A 288
SER A 184
ILE A 179
MET A 175
 None
 1.09A 5igyA-3qufA:
undetectable		 5igyA-3qufA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		3 / 3 LYS A 167
GLN A 373
ASN A 369
 None
 1.04A 5l2tA-3qufA:
undetectable		 5l2tA-3qufA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		3 / 3 THR A  39
ALA A 325
LYS A 327
 None
 0.46A 6fgcA-3qufA:
undetectable		 6fgcA-3qufA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		3 / 3 THR A  39
ALA A 325
LYS A 327
 None
 0.49A 6fgdA-3qufA:
undetectable		 6fgdA-3qufA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 7 GLY A  73
TYR A  72
ASN A  50
GLU A  54
GLY A  53
 None
 1.29A 6n7fA-3qufA:
undetectable		 6n7fA-3qufA:
17.84