SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qum'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.14A 1usqA-3qumH:
2.1		 1usqA-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqB-3qumH:
undetectable		 1usqB-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqC-3qumH:
2.1		 1usqC-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqD-3qumH:
2.1		 1usqD-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqE-3qumH:
2.1		 1usqE-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.13A 1usqF-3qumH:
2.1		 1usqF-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 3qum PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens) 		4 / 4 LEU P  53
PRO P 111
ILE P 242
LEU P 105
 None
 1.11A 1ya4B-3qumP:
undetectable		 1ya4B-3qumP:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3qum FAB 5D5A5 HEAVY
CHAIN
PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens;
Mus
musculus) 		4 / 8 SER B  30
SER B  53
SER P  86
GLN P  50
 None
 0.97A 2cmlB-3qumB:
undetectable		 2cmlB-3qumB:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.16A 2jkjE-3qumH:
1.2		 2jkjE-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.16A 2jklA-3qumH:
undetectable		 2jklA-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.17A 2jklC-3qumH:
undetectable		 2jklC-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.16A 2jklD-3qumH:
2.1		 2jklD-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.16A 2jklE-3qumH:
undetectable		 2jklE-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3qum FAB 5D3D11 HEAVY
CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.16A 2jklF-3qumH:
2.1		 2jklF-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 3qum PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens) 		5 / 9 LEU P  53
ILE P 212
GLY P 196
LEU P 105
SER P  88
 None
 1.05A 3ai9X-3qumP:
undetectable		 3ai9X-3qumP:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3qum FAB 5D5A5 HEAVY
CHAIN
(Mus
musculus) 		3 / 3 SER B 162
SER B 161
HIS B 165
 None
 0.52A 3mzeA-3qumB:
1.9		 3mzeA-3qumB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3qum PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens) 		3 / 3 GLU P 218
GLY P 216
SER P 195
 None
 0.50A 4b53B-3qumP:
undetectable		 4b53B-3qumP:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3qum FAB 5D5A5 HEAVY
CHAIN
(Mus
musculus) 		5 / 10 VAL B 110
ALA B   9
SER B  17
VAL B 112
THR B 108
 None
 1.49A 4eilB-3qumB:
undetectable		 4eilB-3qumB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qum PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens) 		5 / 12 GLY P 133
ILE P 144
GLY P 142
GLY P 140
THR P 135
 None
 0.96A 5eqbA-3qumP:
undetectable		 5eqbA-3qumP:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 3qum FAB 5D5A5 HEAVY
CHAIN
PROSTATE-SPECIFIC
ANTIGEN
(Mus
musculus;
Homo
sapiens) 		4 / 5 ARG P 107
SER B  30
SER B  53
SER B  28
 None
 1.28A 5hswA-3qumP:
undetectable		 5hswA-3qumP:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3qum PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens) 		5 / 12 GLY P 140
PHE P 149
ILE P  65
GLY P 196
GLY P 197
 None
 0.88A 5koxA-3qumP:
undetectable		 5koxA-3qumP:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHG_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3qum FAB 5D3D11 HEAVY
CHAIN
PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens;
Mus
musculus) 		5 / 12 ASP P 122
SER H  76
ARG H  94
PRO H  52
ILE H  29
 GAL  P 301 ( 3.9A)
GAL  P 301 ( 4.9A)
None
None
None
 1.42A 5uhgC-3qumP:
undetectable		 5uhgC-3qumP:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3qum PROSTATE-SPECIFIC
ANTIGEN
(Homo
sapiens) 		4 / 8 SER P  86
PHE P  89
HIS P  48
ILE P 242
 None
 0.92A 5vkqB-3qumP:
undetectable
5vkqC-3qumP:
undetectable		 5vkqB-3qumP:
9.24
5vkqC-3qumP:
9.24