SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3quw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  36
ILE A  52
PRO A 130
GLU A 136
 None
 0.39A 1oniA-3quwA:
22.5
1oniB-3quwA:
22.4		 1oniA-3quwA:
32.68
1oniB-3quwA:
32.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  36
ILE A  52
PRO A 130
GLU A 136
 None
 0.33A 1oniB-3quwA:
22.4
1oniC-3quwA:
22.5		 1oniB-3quwA:
32.68
1oniC-3quwA:
32.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  36
ILE A  52
PRO A 130
GLU A 136
 None
 0.24A 1oniA-3quwA:
22.5
1oniC-3quwA:
22.5		 1oniA-3quwA:
32.68
1oniC-3quwA:
32.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  36
ILE A  52
PRO A 130
GLU A 136
 None
 0.32A 1oniD-3quwA:
22.6
1oniE-3quwA:
22.7		 1oniD-3quwA:
32.68
1oniE-3quwA:
32.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  36
ILE A  52
PRO A 130
GLU A 136
 None
 0.41A 1oniG-3quwA:
22.5
1oniI-3quwA:
22.4		 1oniG-3quwA:
32.68
1oniI-3quwA:
32.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 6 GLU A  70
PHE A 106
TYR A 110
HIS A 113
 None
 1.40A 4uciA-3quwA:
undetectable		 4uciA-3quwA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3quw PROTEIN MMF1
(Saccharomyces
cerevisiae) 		4 / 7 GLU A  70
PHE A 106
TYR A 110
HIS A 113
 None
 1.38A 4uciB-3quwA:
undetectable		 4uciB-3quwA:
15.09