SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3qv0 MITOCHONDRIAL ACIDIC
PROTEIN MAM33
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  88
GLU A  96
ALA A  97
HIS A 110
VAL A 111
 None
 1.03A 4e0fA-3qv0A:
undetectable		 4e0fA-3qv0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 3qv0 MITOCHONDRIAL ACIDIC
PROTEIN MAM33
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 234
ASN A 235
LEU A  81
LEU A  88
ALA A  97
 None
 1.23A 4rtbA-3qv0A:
undetectable		 4rtbA-3qv0A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3qv0 MITOCHONDRIAL ACIDIC
PROTEIN MAM33
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 236
GLU A 237
TYR A  84
PHE A  80
 None
 1.35A 4twdG-3qv0A:
undetectable
4twdH-3qv0A:
undetectable		 4twdG-3qv0A:
22.15
4twdH-3qv0A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3qv0 MITOCHONDRIAL ACIDIC
PROTEIN MAM33
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 265
PHE A 264
LEU A 258
LEU A  57
VAL A  53
 None
 1.17A 5tudA-3qv0A:
undetectable		 5tudA-3qv0A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3qv0 MITOCHONDRIAL ACIDIC
PROTEIN MAM33
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 102
GLY A 106
GLU A 107
 None
 0.39A 6fgdA-3qv0A:
undetectable		 6fgdA-3qv0A:
16.63