SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		3 / 3 TRP A 251
ARG A  34
THR A 245
 None
 0.93A 1df7A-3qvfA:
1.1		 1df7A-3qvfA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 5 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.46A 1p6kB-3qvfA:
undetectable		 1p6kB-3qvfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 4 VAL A  29
ALA A  33
LEU A  49
PHE A  36
 None
 1.13A 1q97B-3qvfA:
undetectable		 1q97B-3qvfA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 5 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.46A 1rs6B-3qvfA:
undetectable		 1rs6B-3qvfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.33A 1v8bA-3qvfA:
undetectable		 1v8bA-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.28A 1v8bA-3qvfA:
undetectable		 1v8bA-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.33A 1v8bB-3qvfA:
undetectable		 1v8bB-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.27A 1v8bB-3qvfA:
undetectable		 1v8bB-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  53
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.29A 1v8bD-3qvfA:
2.2		 1v8bD-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.34A 1v8bD-3qvfA:
2.2		 1v8bD-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.29A 1v8bD-3qvfA:
2.2		 1v8bD-3qvfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 5 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.45A 1zzuB-3qvfA:
undetectable		 1zzuB-3qvfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 7 THR A 168
SER A 149
SER A 148
LEU A 201
 None
FV1  A4001 (-2.6A)
FV1  A4001 (-2.6A)
ADP  A1260 (-4.1A)
 1.04A 2hdnE-3qvfA:
undetectable
2hdnF-3qvfA:
2.4
2hdnH-3qvfA:
undetectable		 2hdnE-3qvfA:
12.24
2hdnF-3qvfA:
21.49
2hdnH-3qvfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 7 SER A 148
LEU A 201
THR A 168
SER A 149
 FV1  A4001 (-2.6A)
ADP  A1260 (-4.1A)
None
FV1  A4001 (-2.6A)
 1.02A 2hdnF-3qvfA:
2.4
2hdnG-3qvfA:
undetectable
2hdnH-3qvfA:
undetectable		 2hdnF-3qvfA:
21.49
2hdnG-3qvfA:
12.24
2hdnH-3qvfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		3 / 3 LEU A 157
PRO A 158
ARG A 151
 None
 0.61A 2qd5A-3qvfA:
3.0		 2qd5A-3qvfA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.31A 3ce6D-3qvfA:
2.3		 3ce6D-3qvfA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.33A 3ce6D-3qvfA:
2.3		 3ce6D-3qvfA:
20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		8 / 8 GLY A  52
GLY A  53
GLY A  57
HIS A  58
ILE A  61
SER A 148
SER A 149
THR A 210
 FV1  A4001 (-3.5A)
FV1  A4001 (-3.2A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
None
FV1  A4001 (-2.6A)
FV1  A4001 (-2.6A)
FV1  A4001 (-2.8A)
 0.16A 3d41A-3qvfA:
47.5		 3d41A-3qvfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 8 GLY A  54
GLY A  57
HIS A  58
ILE A  61
THR A 210
 FV1  A4001 (-3.2A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
None
FV1  A4001 (-2.8A)
 0.96A 3d41A-3qvfA:
47.5		 3d41A-3qvfA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.35A 3n58C-3qvfA:
2.4		 3n58C-3qvfA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.33A 3n58C-3qvfA:
2.4		 3n58C-3qvfA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 4 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.48A 3n62A-3qvfA:
0.0		 3n62A-3qvfA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 4 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.45A 3n65A-3qvfA:
0.3		 3n65A-3qvfA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 4 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.44A 3n66A-3qvfA:
0.4		 3n66A-3qvfA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.31A 3ondA-3qvfA:
undetectable		 3ondA-3qvfA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.29A 3ondA-3qvfA:
undetectable		 3ondA-3qvfA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.29A 3ondB-3qvfA:
2.2		 3ondB-3qvfA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.29A 3ondB-3qvfA:
2.2		 3ondB-3qvfA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 8 GLU A  77
GLU A  81
LYS A  84
ARG A  85
 None
 0.88A 4bqfB-3qvfA:
3.4		 4bqfB-3qvfA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 10 ILE A 260
ALA A 219
THR A 170
ILE A 232
THR A 222
 None
None
ADP  A1260 (-3.6A)
None
None
 1.31A 4km0A-3qvfA:
undetectable		 4km0A-3qvfA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 6 ARG A  46
GLY A  45
ASP A   4
ARG A 121
 None
 0.84A 4lajA-3qvfA:
undetectable
4lajB-3qvfA:
undetectable		 4lajA-3qvfA:
18.02
4lajB-3qvfA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.30A 5axdA-3qvfA:
undetectable		 5axdA-3qvfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.33A 5axdA-3qvfA:
undetectable		 5axdA-3qvfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.30A 5axdC-3qvfA:
undetectable		 5axdC-3qvfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.32A 5axdC-3qvfA:
undetectable		 5axdC-3qvfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ILE A  50
GLY A  12
SER A 148
GLY A 134
LEU A 102
 None
FV1  A4001 ( 3.3A)
FV1  A4001 (-2.6A)
FV1  A4001 ( 4.0A)
None
 1.03A 5i75A-3qvfA:
undetectable		 5i75A-3qvfA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.37A 5m5kB-3qvfA:
undetectable		 5m5kB-3qvfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.37A 5m5kB-3qvfA:
undetectable		 5m5kB-3qvfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.32A 5m66A-3qvfA:
2.3		 5m66A-3qvfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.31A 5m66A-3qvfA:
2.3		 5m66A-3qvfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.30A 5m66C-3qvfA:
2.2		 5m66C-3qvfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.35A 5m66C-3qvfA:
2.2		 5m66C-3qvfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 VAL A  95
ASP A  96
LEU A  39
PRO A 130
LEU A 124
 None
 1.30A 5nd4B-3qvfA:
undetectable		 5nd4B-3qvfA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.27A 5utuF-3qvfA:
undetectable		 5utuF-3qvfA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.27A 5utuF-3qvfA:
undetectable		 5utuF-3qvfA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 5 GLY A  12
TRP A  86
VAL A  82
SER A 149
 FV1  A4001 ( 3.3A)
None
None
FV1  A4001 (-2.6A)
 1.46A 5vunA-3qvfA:
undetectable		 5vunA-3qvfA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A  26
LEU A 241
ASP A 236
LEU A 169
LEU A  90
 None
 0.88A 6b0lB-3qvfA:
undetectable		 6b0lB-3qvfA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 6 ASP A 173
LEU A 241
SER A 239
PHE A 243
 None
 1.20A 6ekuA-3qvfA:
undetectable		 6ekuA-3qvfA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  54
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.2A)
FV1  A4001 (-4.0A)
 1.28A 6f3nB-3qvfA:
2.4		 6f3nB-3qvfA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		5 / 12 ASP A 150
THR A 215
ASP A 208
GLY A  57
HIS A  58
 MG  A5000 (-4.0A)
None
ADP  A1260 ( 3.9A)
FV1  A4001 (-3.4A)
FV1  A4001 (-4.0A)
 1.27A 6f3nB-3qvfA:
2.4		 6f3nB-3qvfA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3qvf FOMA PROTEIN
(Streptomyces
wedmorensis) 		4 / 6 TRP A 145
ALA A  69
LEU A  72
ALA A 136
 None
 1.01A 6fosB-3qvfA:
undetectable		 6fosB-3qvfA:
15.38