SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qvl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 148
GLY A 185
GLY A 186
THR A 119
ASN A  12
 None
5HY  A   1 (-3.8A)
None
5HY  A   1 (-3.6A)
5HY  A   1 (-4.0A)
 1.13A 1likA-3qvlA:
undetectable		 1likA-3qvlA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
THR A 118
ALA A 188
GLY A  81
SER A  79
 None
5HY  A   1 (-4.4A)
None
None
5HY  A   1 (-3.1A)
 1.31A 1nbiC-3qvlA:
undetectable		 1nbiC-3qvlA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 10 LEU A  61
ALA A  88
ILE A  77
PRO A  83
ILE A   9
 None
 1.10A 1yi4A-3qvlA:
undetectable		 1yi4A-3qvlA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		4 / 8 PRO A  83
SER A  79
VAL A  58
GLY A  59
 None
5HY  A   1 (-3.1A)
None
None
 1.04A 2qd3A-3qvlA:
3.4		 2qd3A-3qvlA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  78
ALA A  88
GLY A  67
ILE A  35
THR A  18
 None
 0.99A 3c6gA-3qvlA:
undetectable		 3c6gA-3qvlA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 10 LEU A  85
ASP A  82
ALA A 100
GLY A 185
ILE A  21
 None
None
None
5HY  A   1 (-3.8A)
None
 1.28A 3ogpB-3qvlA:
undetectable		 3ogpB-3qvlA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		4 / 5 PRO A  83
ASP A  82
ILE A   9
VAL A 206
 None
 1.31A 4hytA-3qvlA:
undetectable		 4hytA-3qvlA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		4 / 8 PRO A  83
SER A  79
VAL A  58
GLY A  59
 None
5HY  A   1 (-3.1A)
None
None
 0.95A 4mk4A-3qvlA:
3.7		 4mk4A-3qvlA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		4 / 8 ILE A   6
ALA A  24
VAL A  28
VAL A  76
 None
 0.82A 5ecnD-3qvlA:
undetectable		 5ecnD-3qvlA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 237
PHE A 241
LEU A 244
ILE A   9
ALA A  87
 None
 1.18A 5ienB-3qvlA:
undetectable		 5ienB-3qvlA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		4 / 8 LEU A  85
VAL A  96
ARG A  89
ILE A  64
 None
 0.82A 5v0vA-3qvlA:
undetectable		 5v0vA-3qvlA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		6 / 12 LEU A  85
ASP A  82
GLY A  81
GLY A 205
VAL A  96
ILE A  77
 None
 1.44A 6dilB-3qvlA:
undetectable		 6dilB-3qvlA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		6 / 12 LEU A  85
ASP A  82
GLY A  81
ILE A  21
VAL A  96
ILE A  77
 None
 1.43A 6dilB-3qvlA:
undetectable		 6dilB-3qvlA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3qvl PUTATIVE HYDANTOIN
RACEMASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A   6
GLY A  74
GLY A  94
ILE A  97
VAL A 210
 None
 1.02A 6iftA-3qvlA:
undetectable		 6iftA-3qvlA:
24.51