SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qvn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 0.96A 1d4fB-3qvnA:
undetectable		 1d4fB-3qvnA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 ILE A 137
ALA A 200
LEU A  87
ALA A  88
ILE A 167
 None
 1.23A 1g5yB-3qvnA:
undetectable		 1g5yB-3qvnA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 ALA A  88
GLY A  94
GLY A  95
ILE A  13
ASP A  14
 None
 0.93A 1sqfA-3qvnA:
undetectable		 1sqfA-3qvnA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		4 / 5 VAL A  90
GLY A  94
VAL A 194
TRP A 197
 None
 1.24A 1tkqB-3qvnA:
undetectable		 1tkqB-3qvnA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 11 GLY A 133
SER A 132
HIS A 174
ILE A 169
ALA A 135
 None
None
MN  A 207 (-3.0A)
None
None
 1.47A 2a58A-3qvnA:
undetectable
2a58E-3qvnA:
undetectable		 2a58A-3qvnA:
23.22
2a58E-3qvnA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 11 ILE A 169
ALA A 135
GLY A 133
SER A 132
HIS A 174
 None
None
None
None
MN  A 207 (-3.0A)
 1.47A 2a58C-3qvnA:
undetectable
2a58D-3qvnA:
undetectable		 2a58C-3qvnA:
23.22
2a58D-3qvnA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		6 / 12 SER A 132
GLN A 155
LEU A  87
HIS A  80
ILE A  28
ALA A 175
 None
None
None
MN  A 207 (-3.4A)
None
MN  A 207 ( 4.9A)
 1.22A 2bxcA-3qvnA:
undetectable		 2bxcA-3qvnA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		4 / 8 PRO A  98
ILE A 108
TRP A 192
ILE A 137
 None
 0.90A 3sfeB-3qvnA:
undetectable
3sfeC-3qvnA:
undetectable		 3sfeB-3qvnA:
22.81
3sfeC-3qvnA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		4 / 7 ILE A  24
TYR A 187
PHE A  83
ASN A  86
 None
 1.38A 4o7gA-3qvnA:
undetectable
4o7gB-3qvnA:
undetectable		 4o7gA-3qvnA:
20.63
4o7gB-3qvnA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		4 / 6 ILE A  24
TYR A 187
PHE A  83
ASN A  86
 None
 1.39A 4o7gB-3qvnA:
undetectable		 4o7gB-3qvnA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		4 / 8 PHE A  83
TRP A 134
ASN A  86
ILE A 119
 None
 0.94A 4qoiA-3qvnA:
undetectable
4qoiB-3qvnA:
undetectable		 4qoiA-3qvnA:
19.50
4qoiB-3qvnA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		4 / 7 ILE A   8
GLY A  75
THR A 157
LEU A  82
 None
 1.01A 5esmA-3qvnA:
undetectable		 5esmA-3qvnA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.01A 5hm8A-3qvnA:
undetectable		 5hm8A-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.00A 5hm8B-3qvnA:
undetectable		 5hm8B-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.00A 5hm8C-3qvnA:
undetectable		 5hm8C-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.01A 5hm8D-3qvnA:
undetectable		 5hm8D-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.00A 5hm8E-3qvnA:
undetectable		 5hm8E-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.01A 5hm8F-3qvnA:
undetectable		 5hm8F-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.01A 5hm8G-3qvnA:
undetectable		 5hm8G-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.01A 5hm8H-3qvnA:
undetectable		 5hm8H-3qvnA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 GLY A 133
TRP A 172
TYR A 187
ASN A 123
THR A 122
 None
 1.07A 5lsuA-3qvnA:
undetectable		 5lsuA-3qvnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 GLY A 133
TRP A 172
TYR A 187
ASN A 123
THR A 122
 None
 1.03A 5lsuB-3qvnA:
undetectable		 5lsuB-3qvnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.12A 6f3mA-3qvnA:
undetectable		 6f3mA-3qvnA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.12A 6f3mB-3qvnA:
undetectable		 6f3mB-3qvnA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.11A 6f3mC-3qvnA:
undetectable		 6f3mC-3qvnA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)		 3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE
(Candida
albicans) 		5 / 12 HIS A  80
ASP A 170
HIS A 174
GLY A  75
PHE A 136
 MN  A 207 (-3.4A)
MN  A 207 (-2.7A)
MN  A 207 (-3.0A)
None
None
 1.11A 6f3mD-3qvnA:
undetectable		 6f3mD-3qvnA:
19.35