SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qvq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		4 / 7 ASN A  24
THR A  64
TRP A  86
ASP A  57
 None
 1.00A 1bu5A-3qvqA:
undetectable		 1bu5A-3qvqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		4 / 8 ASN A  24
THR A  64
TRP A  86
ASP A  57
 None
 1.01A 1bu5B-3qvqA:
undetectable		 1bu5B-3qvqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 12 LEU A 224
VAL A  11
ILE A  37
SER A  17
SER A  18
 None
 0.99A 1s19A-3qvqA:
undetectable		 1s19A-3qvqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 11 ILE A  96
ILE A  54
TYR A  71
GLY A  68
PHE A  55
 None
None
None
CL  A 257 (-3.9A)
None
 1.23A 2azyA-3qvqA:
undetectable		 2azyA-3qvqA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 9 LEU A 113
LEU A 146
LEU A 145
ILE A 165
LEU A 117
 None
 1.21A 2f7aB-3qvqA:
undetectable		 2f7aB-3qvqA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		3 / 3 GLU A 116
HIS A  14
GLU A  41
 G3P  A 301 ( 2.3A)
G3P  A 301 (-4.0A)
MG  A 310 ( 2.6A)
 0.77A 2x45B-3qvqA:
undetectable		 2x45B-3qvqA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		3 / 3 GLU A 116
HIS A  14
GLU A  41
 G3P  A 301 ( 2.3A)
G3P  A 301 (-4.0A)
MG  A 310 ( 2.6A)
 0.77A 2x45C-3qvqA:
undetectable		 2x45C-3qvqA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		4 / 8 LEU A 135
SER A 131
VAL A  44
ALA A 102
 None
 0.99A 3ax9A-3qvqA:
undetectable		 3ax9A-3qvqA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 12 LEU A 155
GLY A 168
SER A 148
LEU A 182
ALA A 173
 None
None
G3P  A 301 ( 4.4A)
None
None
 1.08A 3ou6A-3qvqA:
undetectable		 3ou6A-3qvqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 12 LEU A 155
GLY A 168
SER A 148
LEU A 182
ALA A 173
 None
None
G3P  A 301 ( 4.4A)
None
None
 1.08A 3ou6B-3qvqA:
undetectable		 3ou6B-3qvqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 12 LEU A 155
GLY A 168
SER A 148
LEU A 182
ALA A 173
 None
None
G3P  A 301 ( 4.4A)
None
None
 1.09A 3ou6C-3qvqA:
undetectable		 3ou6C-3qvqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 12 LEU A 155
GLY A 168
SER A 148
LEU A 182
ALA A 173
 None
None
G3P  A 301 ( 4.4A)
None
None
 1.10A 3ou7B-3qvqA:
undetectable		 3ou7B-3qvqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 12 LEU A 155
GLY A 168
SER A 148
LEU A 182
ALA A 173
 None
None
G3P  A 301 ( 4.4A)
None
None
 1.08A 3ou7C-3qvqA:
undetectable		 3ou7C-3qvqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		3 / 3 HIS A  56
GLU A  41
ASN A 170
 G3P  A 301 (-3.9A)
MG  A 310 ( 2.6A)
G3P  A 301 (-3.8A)
 1.04A 4bupB-3qvqA:
undetectable		 4bupB-3qvqA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		4 / 7 ILE A  96
PRO A  97
GLY A  16
GLN A  20
 None
 0.88A 4g0uB-3qvqA:
undetectable		 4g0uB-3qvqA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		4 / 6 ASP A  43
ASP A 237
ASN A  24
GLU A 116
 MG  A 310 ( 2.6A)
None
None
G3P  A 301 ( 2.3A)
 1.23A 4gkhJ-3qvqA:
undetectable		 4gkhJ-3qvqA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		5 / 11 SER A 236
THR A 216
ALA A 233
ALA A 223
ASP A 219
 None
 1.35A 5bxnV-3qvqA:
undetectable
5bxnW-3qvqA:
undetectable		 5bxnV-3qvqA:
24.54
5bxnW-3qvqA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		4 / 5 LEU A 213
LYS A 211
LEU A   8
TYR A   5
 None
 1.17A 5ki6A-3qvqA:
undetectable		 5ki6A-3qvqA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		3 / 3 TYR A   5
SER A   3
TRP A  39
 None
 1.07A 5n8jD-3qvqA:
undetectable		 5n8jD-3qvqA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3qvq PHOSPHODIESTERASE
OLEI02445
(Oleispira
antarctica) 		3 / 3 VAL A 234
LYS A  38
MET A 111
 None
CL  A 259 ( 4.8A)
None
 0.99A 5nknA-3qvqA:
undetectable		 5nknA-3qvqA:
15.45