SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 12 LEU A  58
LEU A 189
GLY A 212
HIS A 213
LEU A 208
 None
 1.25A 1g50B-3qvuA:
undetectable		 1g50B-3qvuA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 11 LEU A  58
LEU A 189
GLY A 212
HIS A 213
LEU A 208
 None
 1.25A 1g50C-3qvuA:
undetectable		 1g50C-3qvuA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		3 / 4 VAL A 137
TRP A 172
TRP A 264
 None
 1.30A 1gmkA-3qvuA:
undetectable
1gmkB-3qvuA:
undetectable		 1gmkA-3qvuA:
4.78
1gmkB-3qvuA:
4.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_A_LDPA297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		6 / 9 PHE A  24
PRO A  47
PHE A  81
LYS A 106
HIS A 108
HIS A 149
 None
None
NPO  A 296 ( 4.7A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.6A)
 0.41A 2a3rA-3qvuA:
48.8		 2a3rA-3qvuA:
91.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_A_LDPA297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 9 PHE A  81
LYS A 106
HIS A 108
ALA A 146
HIS A 149
 NPO  A 296 ( 4.7A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.6A)
 1.45A 2a3rA-3qvuA:
48.8		 2a3rA-3qvuA:
91.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_B_LDPB297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		6 / 9 PHE A  24
PRO A  47
PHE A  81
LYS A 106
HIS A 108
HIS A 149
 None
None
NPO  A 296 ( 4.7A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.6A)
 0.39A 2a3rB-3qvuA:
48.8		 2a3rB-3qvuA:
91.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_B_LDPB297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 9 PHE A  81
LYS A 106
HIS A 108
ALA A 146
HIS A 149
 NPO  A 296 ( 4.7A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.6A)
 1.44A 2a3rB-3qvuA:
48.8		 2a3rB-3qvuA:
91.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 5 LEU A  82
LEU A  31
LEU A 113
LEU A 114
 None
 1.02A 2ab2B-3qvuA:
undetectable		 2ab2B-3qvuA:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		8 / 10 PHE A  24
PRO A  47
LYS A  48
LYS A 106
HIS A 108
ALA A 146
VAL A 148
MET A 145
 None
None
A3P  A2001 (-3.1A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.7A)
None
 1.34A 2d06A-3qvuA:
48.8		 2d06A-3qvuA:
97.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		9 / 10 PHE A  24
PRO A  47
LYS A  48
LYS A 106
HIS A 108
PHE A 142
ALA A 146
VAL A 148
MET A 248
 None
None
A3P  A2001 (-3.1A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.8A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.7A)
NPO  A 296 ( 4.3A)
 0.42A 2d06A-3qvuA:
48.8		 2d06A-3qvuA:
97.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 10 PHE A  84
LYS A  48
ALA A 146
VAL A 148
MET A 145
 None
A3P  A2001 (-3.1A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.7A)
None
 1.33A 2d06A-3qvuA:
48.8		 2d06A-3qvuA:
97.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 10 PHE A  84
LYS A  48
PHE A 142
ALA A 146
VAL A 148
 None
A3P  A2001 (-3.1A)
NPO  A 296 (-4.8A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.7A)
 1.08A 2d06A-3qvuA:
48.8		 2d06A-3qvuA:
97.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		7 / 10 PHE A  24
PRO A  47
LYS A 106
HIS A 108
ALA A 146
VAL A 148
MET A 145
 None
None
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.7A)
None
 1.43A 2d06B-3qvuA:
48.9		 2d06B-3qvuA:
97.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		9 / 10 PHE A  24
PRO A  47
LYS A 106
HIS A 108
PHE A 142
ALA A 146
VAL A 148
TYR A 240
MET A 248
 None
None
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.8A)
NPO  A 296 ( 4.0A)
NPO  A 296 (-4.7A)
None
NPO  A 296 ( 4.3A)
 0.39A 2d06B-3qvuA:
48.9		 2d06B-3qvuA:
97.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 7 TYR A  46
TYR A 139
GLY A 165
TYR A 143
 None
 1.07A 2g72B-3qvuA:
undetectable		 2g72B-3qvuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 5 TRP A 155
GLY A 153
PRO A 152
PHE A 158
 None
 1.21A 2rezA-3qvuA:
undetectable		 2rezA-3qvuA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 11 LEU A  58
LEU A 189
GLY A 212
HIS A 213
LEU A 208
 None
 1.28A 3uudA-3qvuA:
undetectable		 3uudA-3qvuA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 12 VAL A 167
GLY A 165
VAL A 164
SER A 157
PRO A 152
 None
 1.33A 4bvaA-3qvuA:
undetectable		 4bvaA-3qvuA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 12 VAL A 167
GLY A 165
VAL A 164
SER A 157
PRO A 152
 None
 1.33A 4bvaB-3qvuA:
undetectable		 4bvaB-3qvuA:
23.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 9 PHE A  81
HIS A 108
PHE A 142
ILE A 243
 NPO  A 296 ( 4.7A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.8A)
None
 0.92A 4jvlA-3qvuA:
43.3		 4jvlA-3qvuA:
50.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		6 / 9 PHE A  81
LYS A 106
HIS A 108
PHE A 142
ILE A 247
MET A 248
 NPO  A 296 ( 4.7A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.8A)
None
NPO  A 296 ( 4.3A)
 0.45A 4jvlA-3qvuA:
43.3		 4jvlA-3qvuA:
50.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_B_ESTB302_1
(ESTROGEN
SULFOTRANSFERASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		6 / 9 PHE A  81
LYS A 106
HIS A 108
PHE A 142
ILE A 247
MET A 248
 NPO  A 296 ( 4.7A)
NPO  A 296 (-3.0A)
NPO  A 296 (-3.7A)
NPO  A 296 (-4.8A)
None
NPO  A 296 ( 4.3A)
 0.49A 4jvlB-3qvuA:
42.8		 4jvlB-3qvuA:
50.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		5 / 12 VAL A 220
ILE A 207
VAL A 211
LEU A 208
LEU A  58
 None
 1.39A 4m11C-3qvuA:
undetectable		 4m11C-3qvuA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 6 PRO A  74
ILE A 243
PHE A  84
THR A  95
 None
 1.12A 4xe5A-3qvuA:
undetectable		 4xe5A-3qvuA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		3 / 3 TYR A 280
TYR A 127
SER A  49
 None
 0.98A 5iktB-3qvuA:
undetectable		 5iktB-3qvuA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 8 PHE A  76
ILE A  89
GLY A  92
PHE A  84
 None
 0.87A 5x5qD-3qvuA:
undetectable		 5x5qD-3qvuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 8 LEU A 191
VAL A 128
VAL A 126
ILE A  57
 None
 0.75A 5y9mA-3qvuA:
undetectable		 5y9mA-3qvuA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_2
(GLUCOAMYLASE P)		 3qvu SULFOTRANSFERASE 1A1
(Homo
sapiens) 		4 / 4 TRP A  53
GLU A 203
GLU A 194
LEU A 295
 A3P  A2001 (-3.3A)
None
None
None
 1.35A 6fhwB-3qvuA:
undetectable		 6fhwB-3qvuA:
13.18