SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qwb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 307
THR A 324
SER A 321
GLN A 132
 None
None
None
NDP  A 335 (-3.6A)
 1.38A 1eiiA-3qwbA:
undetectable		 1eiiA-3qwbA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A 107
GLU A  37
GLU A  36
 None
 0.70A 1eqbD-3qwbA:
3.1		 1eqbD-3qwbA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A 107
GLU A  37
GLU A  36
 None
 0.71A 1eqbB-3qwbA:
3.4		 1eqbB-3qwbA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 290
ILE A 277
GLN A 132
ALA A 136
SER A 138
 None
None
NDP  A 335 (-3.6A)
None
None
 1.35A 1fm4A-3qwbA:
undetectable		 1fm4A-3qwbA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 237
LEU A 234
ALA A 235
ILE A 177
LEU A 210
 None
 1.29A 1g50A-3qwbA:
undetectable		 1g50A-3qwbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 209
ILE A 205
ILE A 232
PHE A 155
VAL A 218
 None
 1.06A 1qhyA-3qwbA:
undetectable		 1qhyA-3qwbA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 209
ILE A 205
PHE A 155
VAL A 218
LEU A 237
 None
 1.04A 1qhyA-3qwbA:
undetectable		 1qhyA-3qwbA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 194
LEU A 197
ALA A 158
ALA A 157
 None
 0.69A 3r9tA-3qwbA:
undetectable		 3r9tA-3qwbA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 222
ALA A 136
THR A 140
LEU A 169
 None
 1.06A 3t3sC-3qwbA:
undetectable		 3t3sC-3qwbA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 129
PRO A 110
ILE A 277
LEU A 273
ILE A  94
 None
None
None
NDP  A 335 (-4.8A)
None
 1.03A 4dt8B-3qwbA:
undetectable		 4dt8B-3qwbA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 160
LEU A 163
ILE A 164
ILE A 301
 NDP  A 335 (-3.3A)
None
None
None
 0.45A 4em2A-3qwbA:
undetectable		 4em2A-3qwbA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 129
ASN A  48
GLU A  70
MET A 171
 None
 1.24A 4g0vB-3qwbA:
1.5		 4g0vB-3qwbA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  65
TYR A  28
GLY A  68
GLU A  51
 None
 1.17A 5emlA-3qwbA:
5.5		 5emlA-3qwbA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3qwb PROBABLE QUINONE
OXIDOREDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 174
PHE A 222
VAL A 152
VAL A 218
TYR A 196
 None
 1.46A 6hu9N-3qwbA:
undetectable		 6hu9N-3qwbA:
22.03