SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qwn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN
(Bacteroides
caccae) 		4 / 4 SER A  95
ILE A  93
VAL A  36
THR A 101
 None
None
None
CL  A 262 ( 4.3A)
 1.10A 1u70A-3qwnA:
undetectable		 1u70A-3qwnA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN
(Bacteroides
caccae) 		4 / 6 SER A  78
GLU A  34
VAL A  59
THR A  48
 None
 1.30A 4lnxA-3qwnA:
undetectable		 4lnxA-3qwnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN
(Bacteroides
caccae) 		3 / 3 ASN A  53
PHE A  35
TYR A 132
 None
 0.88A 4u15A-3qwnA:
undetectable		 4u15A-3qwnA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN
(Bacteroides
caccae) 		5 / 12 LEU A  96
ALA A  56
GLY A  41
ALA A  40
SER A  45
 None
 1.01A 5jw1A-3qwnA:
undetectable		 5jw1A-3qwnA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN
(Bacteroides
caccae) 		4 / 6 GLY A 227
PRO A 226
THR A 203
GLU A 229
 None
 1.13A 5ny7A-3qwnA:
undetectable		 5ny7A-3qwnA:
21.38