SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qwr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3qwr ADNECTIN
(Homo
sapiens) 		5 / 12 ILE D  70
VAL D  72
TYR D  32
TYR D  36
ILE D  59
 None
 1.10A 3vrjA-3qwrD:
4.6
3vrjC-3qwrD:
undetectable		 3vrjA-3qwrD:
17.87
3vrjC-3qwrD:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3qwr ADNECTIN
(Homo
sapiens) 		5 / 12 GLU D  38
ASP D  67
ASN D  91
GLY D  41
SER D  43
 None
 1.49A 4djeB-3qwrD:
undetectable		 4djeB-3qwrD:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3qwr ADNECTIN
(Homo
sapiens) 		5 / 12 GLU D  38
ASP D  67
ASN D  91
GLY D  41
SER D  43
 None
 1.40A 4djfB-3qwrD:
undetectable		 4djfB-3qwrD:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3qwr ADNECTIN
(Homo
sapiens) 		5 / 12 GLU D  38
ASP D  67
GLY D  41
SER D  43
GLN D  46
 None
 1.34A 4djfB-3qwrD:
undetectable		 4djfB-3qwrD:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3qwr ADNECTIN
(Homo
sapiens) 		4 / 7 ILE D  70
VAL D  10
ALA D  13
THR D  14
 None
 0.98A 6cduC-3qwrD:
undetectable
6cduD-3qwrD:
undetectable		 6cduC-3qwrD:
15.38
6cduD-3qwrD:
15.38