SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3qwx CELL DEATH
ABNORMALITY PROTEIN
2
(Caenorhabditis
elegans) 		5 / 12 VAL X  82
LEU X  51
PHE X  99
LEU X 104
THR X 105
 None
 1.33A 5hnxB-3qwxX:
undetectable		 5hnxB-3qwxX:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3qwx CELL DEATH
ABNORMALITY PROTEIN
2
(Caenorhabditis
elegans) 		4 / 5 LEU X  51
VAL X  53
GLU X  55
LEU X 104
 None
 1.01A 5xooB-3qwxX:
undetectable		 5xooB-3qwxX:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3qwx CELL DEATH
ABNORMALITY PROTEIN
2
(Caenorhabditis
elegans) 		4 / 8 ARG X  45
GLU X  48
VAL X  82
ARG X  41
 None
None
None
SO4  X 175 (-3.1A)
 1.29A 6fbvD-3qwxX:
undetectable		 6fbvD-3qwxX:
8.97