SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3qwy CELL DEATH
ABNORMALITY PROTEIN
2
(Caenorhabditis
elegans) 		5 / 11 LEU A  39
LYS A 114
VAL A  33
LEU A  27
PRO A 116
 None
 1.39A 1klmA-3qwyA:
undetectable		 1klmA-3qwyA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3qwy CELL DEATH
ABNORMALITY PROTEIN
2
(Caenorhabditis
elegans) 		4 / 5 LEU A  51
VAL A  53
GLU A  55
LEU A 104
 None
 1.00A 5xooB-3qwyA:
undetectable		 5xooB-3qwyA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3qwy CELL DEATH
ABNORMALITY PROTEIN
2
(Caenorhabditis
elegans) 		5 / 12 ASN A 169
VAL A 121
ILE A 145
PHE A 137
PHE A 127
 None
 1.49A 6j20A-3qwyA:
undetectable		 6j20A-3qwyA:
20.13