SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 5 TYR A  77
GLU A 267
PRO A 162
ASP A 194
 None
FE  A 301 ( 2.6A)
None
FE  A 301 ( 3.2A)
 1.19A 1i7zB-3qxbA:
undetectable		 1i7zB-3qxbA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 9 PHE A 116
GLY A  93
ALA A  84
LEU A  83
GLY A 117
 None
 1.38A 1jb0A-3qxbA:
undetectable		 1jb0A-3qxbA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 8 GLY A  72
GLU A 267
TRP A 141
HIS A 225
 None
FE  A 301 ( 2.6A)
None
FE  A 301 ( 3.3A)
 1.05A 1maaD-3qxbA:
2.6		 1maaD-3qxbA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 9 PHE A 116
GLY A  93
ALA A  84
LEU A  83
GLY A 117
 None
 1.38A 3pcqA-3qxbA:
undetectable		 3pcqA-3qxbA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 5 GLU A 186
THR A 185
THR A 112
HIS A  96
 None
 1.18A 5axaA-3qxbA:
undetectable		 5axaA-3qxbA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 5 GLU A 186
THR A 185
THR A 112
HIS A  96
 None
 1.22A 5axaC-3qxbA:
undetectable		 5axaC-3qxbA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 12 ASP A 139
ALA A 135
ASP A 123
SER A 118
THR A 165
 None
 1.14A 5hfjD-3qxbA:
undetectable		 5hfjD-3qxbA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 12 ASP A 139
ALA A 135
ASP A 123
SER A 118
THR A 165
 None
 1.04A 5hfjE-3qxbA:
undetectable		 5hfjE-3qxbA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 11 PHE A  82
THR A 185
VAL A 189
VAL A 158
MET A 114
 None
 1.44A 5jkwA-3qxbA:
undetectable		 5jkwA-3qxbA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 12 THR A  70
GLY A 113
SER A  76
LEU A  97
ALA A 100
 None
 0.91A 5l0zA-3qxbA:
2.9		 5l0zA-3qxbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 10 THR A  70
GLY A 113
SER A  76
LEU A  97
ALA A 100
 None
 1.03A 5l0zB-3qxbA:
undetectable		 5l0zB-3qxbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 9 PHE A 116
GLY A  93
ALA A  84
LEU A  83
GLY A 117
 None
 1.42A 5l8rA-3qxbA:
undetectable		 5l8rA-3qxbA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 9 ALA A 100
ILE A 101
TYR A  37
ALA A 111
LEU A 153
 None
 0.94A 5mvmA-3qxbA:
undetectable
5mvmE-3qxbA:
undetectable		 5mvmA-3qxbA:
14.05
5mvmE-3qxbA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 6 ALA A 111
LEU A 153
ILE A 101
TYR A  37
 None
 0.86A 5mvmB-3qxbA:
undetectable
5mvmC-3qxbA:
undetectable		 5mvmB-3qxbA:
14.05
5mvmC-3qxbA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		3 / 3 HIS A 197
ASP A 234
HIS A 236
 FE  A 304 ( 3.4A)
MN  A 303 ( 2.4A)
MN  A 303 ( 3.3A)
 0.62A 5oexA-3qxbA:
undetectable		 5oexA-3qxbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		3 / 3 HIS A 197
ASP A 234
HIS A 236
 FE  A 304 ( 3.4A)
MN  A 303 ( 2.4A)
MN  A 303 ( 3.3A)
 0.63A 5oexB-3qxbA:
undetectable		 5oexB-3qxbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		3 / 3 HIS A 197
ASP A 234
HIS A 236
 FE  A 304 ( 3.4A)
MN  A 303 ( 2.4A)
MN  A 303 ( 3.3A)
 0.61A 5oexC-3qxbA:
undetectable		 5oexC-3qxbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		3 / 3 HIS A 197
ASP A 234
HIS A 236
 FE  A 304 ( 3.4A)
MN  A 303 ( 2.4A)
MN  A 303 ( 3.3A)
 0.61A 5oexD-3qxbA:
undetectable		 5oexD-3qxbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		5 / 9 LEU A  20
VAL A  11
LEU A  39
MET A 283
LEU A  28
 None
 1.20A 5og9A-3qxbA:
undetectable		 5og9A-3qxbA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 8 THR A  36
TYR A  37
THR A  40
ARG A  52
 None
None
None
EDO  A 360 ( 3.2A)
 1.39A 5tzoA-3qxbA:
undetectable		 5tzoA-3qxbA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 5 GLY A 196
ARG A 235
ASP A 194
GLN A  34
 None
None
FE  A 301 ( 3.2A)
None
 1.45A 5ubbA-3qxbA:
undetectable		 5ubbA-3qxbA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 6 GLN A  90
PHE A  82
PHE A 116
LEU A 177
 None
 1.04A 5z84P-3qxbA:
undetectable
5z84W-3qxbA:
undetectable		 5z84P-3qxbA:
22.26
5z84W-3qxbA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 6 GLN A  90
PHE A  82
PHE A 116
LEU A 177
 None
 1.03A 5z85P-3qxbA:
undetectable
5z85W-3qxbA:
undetectable		 5z85P-3qxbA:
22.26
5z85W-3qxbA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 6 GLN A  90
PHE A  82
PHE A 116
LEU A 177
 None
 1.09A 5z86C-3qxbA:
undetectable
5z86J-3qxbA:
undetectable		 5z86C-3qxbA:
22.26
5z86J-3qxbA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 6 GLN A  90
PHE A  82
PHE A 116
LEU A 177
 None
 1.03A 5z86P-3qxbA:
undetectable
5z86W-3qxbA:
undetectable		 5z86P-3qxbA:
22.26
5z86W-3qxbA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qxb PUTATIVE XYLOSE
ISOMERASE
(Rhodospirillum
rubrum) 		4 / 6 GLN A  90
PHE A  82
PHE A 116
LEU A 177
 None
 1.05A 5zcpP-3qxbA:
undetectable
5zcpW-3qxbA:
undetectable		 5zcpP-3qxbA:
22.26
5zcpW-3qxbA:
8.71