SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		5 / 10 PRO A 157
GLY A 158
PHE A 178
ARG A 207
GLY A 229
 None
 1.11A 1h4oA-3qxfA:
undetectable
1h4oB-3qxfA:
undetectable		 1h4oA-3qxfA:
19.25
1h4oB-3qxfA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 7 ILE A  76
GLU A  29
TRP A  28
LEU A 338
 None
 1.08A 1j96B-3qxfA:
undetectable		 1j96B-3qxfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		5 / 8 TYR A  59
TYR A 182
ARG A 246
THR A  53
ALA A 114
 None
 1.36A 2a1hA-3qxfA:
undetectable
2a1hB-3qxfA:
undetectable		 2a1hA-3qxfA:
21.28
2a1hB-3qxfA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		5 / 10 TYR A  59
TYR A 182
ARG A 246
THR A  53
ALA A 114
 None
 1.37A 2coiA-3qxfA:
undetectable
2coiB-3qxfA:
undetectable		 2coiA-3qxfA:
19.47
2coiB-3qxfA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		5 / 12 SER A 115
VAL A 119
GLN A 189
THR A 192
PHE A 191
 None
 1.31A 2vdyA-3qxfA:
undetectable		 2vdyA-3qxfA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 8 THR A  80
LEU A 144
GLU A  55
SER A  58
 None
 1.05A 2zw9A-3qxfA:
undetectable		 2zw9A-3qxfA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 8 ASN A 205
THR A 204
LEU A 208
ALA A 188
 None
 0.93A 3hrdA-3qxfA:
undetectable
3hrdB-3qxfA:
undetectable		 3hrdA-3qxfA:
20.44
3hrdB-3qxfA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		5 / 12 SER A 115
VAL A 119
GLN A 189
THR A 192
PHE A 191
 None
 1.35A 4c49B-3qxfA:
undetectable		 4c49B-3qxfA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_2
(SUGAR KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 4 SER A 115
SER A  58
TYR A 182
PRO A  94
 None
 1.27A 4e3aB-3qxfA:
0.0		 4e3aB-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 8 SER A  54
GLU A 152
GLU A 151
GLY A 169
 None
 0.89A 4fgzA-3qxfA:
undetectable
4fgzB-3qxfA:
undetectable		 4fgzA-3qxfA:
22.47
4fgzB-3qxfA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.73A 4k8cA-3qxfA:
undetectable		 4k8cA-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.74A 4kahA-3qxfA:
undetectable		 4kahA-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.74A 4kahB-3qxfA:
undetectable		 4kahB-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.75A 4kanA-3qxfA:
undetectable		 4kanA-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.73A 4kanB-3qxfA:
undetectable		 4kanB-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.74A 4kbeA-3qxfA:
undetectable		 4kbeA-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.75A 4kbeB-3qxfA:
undetectable		 4kbeB-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.71A 4lbgA-3qxfA:
undetectable		 4lbgA-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 182
PRO A  94
 None
 0.73A 4lbgB-3qxfA:
undetectable		 4lbgB-3qxfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 4 SER A  58
SER A  54
GLU A 152
ASP A 116
 None
 1.46A 4ymgA-3qxfA:
undetectable		 4ymgA-3qxfA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		5 / 12 LEU A 163
VAL A 119
GLY A 117
SER A 113
LEU A  93
 None
 1.10A 5ikrA-3qxfA:
undetectable		 5ikrA-3qxfA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 6 TRP A 221
LEU A  97
ASP A 116
GLU A  55
 None
 1.19A 6djzC-3qxfA:
undetectable		 6djzC-3qxfA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3qxf ENDOGLUCANASE
(Escherichia
coli) 		4 / 8 LYS A  24
ARG A 347
VAL A 321
ARG A 349
 None
 1.28A 6fbvD-3qxfA:
undetectable		 6fbvD-3qxfA:
13.05