SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		6 / 12 VAL A   4
ALA A  26
MET A  36
ARG A  74
VAL A  81
ALA A 100
 None
 0.81A 3qxtA-3qxuA:
25.6		 3qxtA-3qxuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		6 / 12 VAL A   4
ALA A  26
SER A  30
MET A  36
VAL A  81
ALA A 100
 None
 0.93A 3qxtA-3qxuA:
25.6		 3qxtA-3qxuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		6 / 12 VAL A   4
ALA A  26
SER A  30
SER A  31
MET A  36
ALA A 100
 None
 1.01A 3qxtA-3qxuA:
25.6		 3qxtA-3qxuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		6 / 12 VAL A   4
ALA A  26
SER A  31
MET A  36
ARG A  74
ALA A 100
 None
 0.70A 3qxtA-3qxuA:
25.6		 3qxtA-3qxuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		8 / 12 VAL A   4
LEU A   6
ALA A  26
SER A  30
MET A  36
VAL A  81
ALA A 100
TYR A 120
 None
 0.86A 3qxtB-3qxuA:
24.9		 3qxtB-3qxuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		9 / 12 VAL A   4
LEU A   6
ALA A  26
SER A  31
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 0.78A 3qxtB-3qxuA:
24.9		 3qxtB-3qxuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 SER A  31
TRP A  34
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 1.41A 3qxvA-3qxuA:
24.2		 3qxvA-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 VAL A   4
ALA A  26
SER A  30
MET A  36
VAL A  81
ALA A 100
TYR A 120
 None
 0.94A 3qxvA-3qxuA:
24.2		 3qxvA-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		8 / 12 VAL A   4
ALA A  26
SER A  31
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 0.86A 3qxvA-3qxuA:
24.2		 3qxvA-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		6 / 12 SER A  30
TRP A  34
MET A  36
VAL A  81
ALA A 100
TYR A 120
 None
 1.49A 3qxvB-3qxuA:
24.1		 3qxvB-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 SER A  31
TRP A  34
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 1.43A 3qxvB-3qxuA:
24.1		 3qxvB-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 VAL A   4
ALA A  26
SER A  30
MET A  36
VAL A  81
ALA A 100
TYR A 120
 None
 0.89A 3qxvB-3qxuA:
24.1		 3qxvB-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		8 / 12 VAL A   4
ALA A  26
SER A  31
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 0.91A 3qxvB-3qxuA:
24.1		 3qxvB-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 11 VAL A   4
ALA A  26
SER A  30
MET A  36
ARG A  74
VAL A  81
ALA A 100
 None
 0.89A 3qxvC-3qxuA:
24.5		 3qxvC-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		6 / 12 SER A  30
TRP A  34
MET A  36
VAL A  81
ALA A 100
TYR A 120
 None
 1.48A 3qxvD-3qxuA:
24.0		 3qxvD-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 SER A  31
TRP A  34
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 1.40A 3qxvD-3qxuA:
24.0		 3qxvD-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 VAL A   4
ALA A  26
SER A  30
MET A  36
VAL A  81
ALA A 100
TYR A 120
 None
 0.90A 3qxvD-3qxuA:
24.0		 3qxvD-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		8 / 12 VAL A   4
ALA A  26
SER A  31
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 0.88A 3qxvD-3qxuA:
24.0		 3qxvD-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		5 / 12 ALA A  26
SER A  30
VAL A  81
ALA A 100
TYR A 120
 None
 0.98A 3qxvE-3qxuA:
20.4		 3qxvE-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 ALA A  26
SER A  31
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 0.88A 3qxvE-3qxuA:
20.4		 3qxvE-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT
(Lama
glama) 		7 / 12 SER A  31
TRP A  34
MET A  36
ARG A  74
VAL A  81
ALA A 100
TYR A 120
 None
 1.44A 3qxvE-3qxuA:
20.4		 3qxvE-3qxuA:
96.03