SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qy2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)		 3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 5 HIS A  43
ARG A  42
ILE A  54
HIS A  96
 None
 1.37A 1osvB-3qy2A:
undetectable		 1osvB-3qy2A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 8 PRO A  55
LEU A  77
GLY A  78
LEU A  13
 None
 0.80A 1ya4A-3qy2A:
undetectable		 1ya4A-3qy2A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 7 PRO A  55
LEU A  77
GLY A  78
LEU A  13
 None
 0.89A 1ya4B-3qy2A:
undetectable		 1ya4B-3qy2A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 HIS A  29
HIS A  43
MET A  45
 None
 1.00A 3mihA-3qy2A:
undetectable		 3mihA-3qy2A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  13
ARG A  18
VAL A  21
LEU A  22
 None
 0.93A 5x7zA-3qy2A:
undetectable		 5x7zA-3qy2A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 102
ARG A  75
ARG A  42
 None
 0.91A 6bplA-3qy2A:
undetectable
6bplB-3qy2A:
undetectable		 6bplA-3qy2A:
22.61
6bplB-3qy2A:
22.61