SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.41A 1d4fD-3qy7A:
undetectable		 1d4fD-3qy7A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 5 HIS A   5
HIS A  42
HIS A 136
ASP A 194
 FE  A 264 (-3.3A)
PO4  A 266 ( 3.3A)
FE  A 263 (-3.4A)
FE  A 264 ( 2.6A)
 0.91A 1e9yB-3qy7A:
13.3		 1e9yB-3qy7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 ASN A  63
ASP A  60
PRO A  10
ALA A  16
ILE A   8
 None
 1.46A 1s14B-3qy7A:
undetectable		 1s14B-3qy7A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.16A 1v7zA-3qy7A:
undetectable		 1v7zA-3qy7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.15A 1v7zB-3qy7A:
undetectable		 1v7zB-3qy7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.16A 1v7zC-3qy7A:
undetectable		 1v7zC-3qy7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.16A 1v7zD-3qy7A:
undetectable		 1v7zD-3qy7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.16A 1v7zE-3qy7A:
undetectable		 1v7zE-3qy7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.16A 1v7zF-3qy7A:
undetectable		 1v7zF-3qy7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   7
HIS A 196
HIS A  42
GLU A 108
ASP A 194
 FE  A 264 ( 3.3A)
MG  A 265 ( 3.3A)
PO4  A 266 ( 3.3A)
FE  A 263 ( 2.9A)
FE  A 264 ( 2.6A)
 1.12A 2pgrA-3qy7A:
10.6		 2pgrA-3qy7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.43A 2zj0B-3qy7A:
undetectable		 2zj0B-3qy7A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.15A 3a6jA-3qy7A:
undetectable		 3a6jA-3qy7A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 7 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.14A 3a6jB-3qy7A:
undetectable		 3a6jB-3qy7A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.13A 3a6jC-3qy7A:
undetectable		 3a6jC-3qy7A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.17A 3a6jE-3qy7A:
undetectable		 3a6jE-3qy7A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 8 GLU A  80
HIS A   7
ASP A 194
HIS A 136
HIS A  42
 FE  A 263 (-2.5A)
FE  A 264 ( 3.3A)
FE  A 264 ( 2.6A)
FE  A 263 (-3.4A)
PO4  A 266 ( 3.3A)
 1.13A 3a6jF-3qy7A:
undetectable		 3a6jF-3qy7A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		3 / 3 PRO A  77
LEU A  97
ARG A  94
 None
 0.71A 3aqiB-3qy7A:
undetectable		 3aqiB-3qy7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.31A 3g1uD-3qy7A:
undetectable		 3g1uD-3qy7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 8 ALA A 158
PHE A 122
LEU A 150
ALA A 118
 None
 0.91A 3hrdA-3qy7A:
undetectable
3hrdB-3qy7A:
undetectable		 3hrdA-3qy7A:
21.02
3hrdB-3qy7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 5 ILE A  83
PHE A 122
ASP A 124
GLU A  88
 None
 1.08A 3kp6A-3qy7A:
undetectable
3kp6B-3qy7A:
undetectable		 3kp6A-3qy7A:
20.39
3kp6B-3qy7A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.32A 3n58A-3qy7A:
2.1		 3n58A-3qy7A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 5 HIS A   5
HIS A  42
HIS A 136
ASP A 194
 FE  A 264 (-3.3A)
PO4  A 266 ( 3.3A)
FE  A 263 (-3.4A)
FE  A 264 ( 2.6A)
 0.94A 4h9mA-3qy7A:
12.3		 4h9mA-3qy7A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.40A 4pgfA-3qy7A:
undetectable		 4pgfA-3qy7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 7 VAL A 133
ILE A  38
ALA A 228
ILE A  37
 None
 0.85A 4uxqA-3qy7A:
undetectable		 4uxqA-3qy7A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A 136
ILE A 107
VAL A 114
GLY A  85
PHE A 122
 FE  A 263 (-3.4A)
None
None
None
None
 1.13A 5byjA-3qy7A:
undetectable		 5byjA-3qy7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 6 ASP A 194
HIS A   7
HIS A 196
HIS A 136
 FE  A 264 ( 2.6A)
FE  A 264 ( 3.3A)
MG  A 265 ( 3.3A)
FE  A 263 (-3.4A)
 0.77A 5ncdA-3qy7A:
4.7
5ncdD-3qy7A:
4.8		 5ncdA-3qy7A:
21.35
5ncdD-3qy7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 6 ASP A 194
HIS A   7
HIS A 196
HIS A 136
 FE  A 264 ( 2.6A)
FE  A 264 ( 3.3A)
MG  A 265 ( 3.3A)
FE  A 263 (-3.4A)
 0.81A 5ncdB-3qy7A:
3.6
5ncdC-3qy7A:
4.6		 5ncdB-3qy7A:
21.35
5ncdC-3qy7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 8 ASP A 194
HIS A   7
HIS A 196
HIS A 136
 FE  A 264 ( 2.6A)
FE  A 264 ( 3.3A)
MG  A 265 ( 3.3A)
FE  A 263 (-3.4A)
 0.91A 5nekB-3qy7A:
4.7		 5nekB-3qy7A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 6 ASP A 194
HIS A   7
HIS A 196
HIS A 136
 FE  A 264 ( 2.6A)
FE  A 264 ( 3.3A)
MG  A 265 ( 3.3A)
FE  A 263 (-3.4A)
 0.77A 5nelA-3qy7A:
4.7
5nelD-3qy7A:
4.5		 5nelA-3qy7A:
21.35
5nelD-3qy7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		4 / 6 HIS A 136
HIS A   7
HIS A 196
LEU A 106
 FE  A 263 (-3.4A)
FE  A 264 ( 3.3A)
MG  A 265 ( 3.3A)
None
 1.06A 5nelB-3qy7A:
4.7
5nelC-3qy7A:
4.8		 5nelB-3qy7A:
21.35
5nelC-3qy7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		3 / 3 HIS A   5
SER A 193
ARG A 201
 FE  A 264 (-3.3A)
None
PO4  A 266 (-2.7A)
 1.01A 5u63A-3qy7A:
undetectable		 5u63A-3qy7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 PHE A 203
ALA A  28
ALA A  26
LEU A  62
MET A  12
 None
 1.36A 6aycA-3qy7A:
undetectable		 6aycA-3qy7A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.35A 6f3nC-3qy7A:
undetectable		 6f3nC-3qy7A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3qy7 TYROSINE-PROTEIN
PHOSPHATASE YWQE
(Bacillus
subtilis) 		5 / 12 HIS A   5
ASP A 194
ASP A  13
LEU A 106
GLY A  78
 FE  A 264 (-3.3A)
FE  A 264 ( 2.6A)
None
None
None
 1.39A 6gbnB-3qy7A:
undetectable		 6gbnB-3qy7A:
19.61