SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		4 / 4 THR A 146
LEU A 150
VAL A 153
LEU A 157
 SO4  A 242 (-3.9A)
None
None
None
 0.82A 1fbmD-3qy9A:
undetectable		 1fbmD-3qy9A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		5 / 9 ILE A   3
GLY A  28
TYR A  40
ALA A  19
GLU A  20
 None
 1.24A 1mrgA-3qy9A:
undetectable		 1mrgA-3qy9A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		4 / 7 LEU A  64
LEU A  76
ASP A  57
GLY A   7
 None
 0.89A 1n13D-3qy9A:
undetectable
1n13E-3qy9A:
undetectable		 1n13D-3qy9A:
20.17
1n13E-3qy9A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		5 / 12 SER A 156
LEU A 117
VAL A 195
PHE A 197
VAL A 121
 None
 1.20A 1q23B-3qy9A:
undetectable		 1q23B-3qy9A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		5 / 10 SER A 156
LEU A 117
VAL A 195
PHE A 197
VAL A 121
 None
 1.17A 1q23E-3qy9A:
undetectable		 1q23E-3qy9A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		5 / 10 SER A 156
LEU A 117
VAL A 195
PHE A 197
VAL A 121
 None
 1.17A 1q23K-3qy9A:
undetectable		 1q23K-3qy9A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		4 / 5 THR A 203
GLU A 194
THR A 132
HIS A 182
 None
 1.41A 3glqA-3qy9A:
7.2		 3glqA-3qy9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		4 / 5 THR A 203
GLU A 194
THR A 132
HIS A 182
 None
 1.40A 3glqB-3qy9A:
6.9		 3glqB-3qy9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		3 / 3 SER A 144
GLY A 145
THR A 146
 SO4  A 242 (-3.7A)
SO4  A 242 (-3.6A)
SO4  A 242 (-3.9A)
 0.22A 3k9wA-3qy9A:
2.2		 3k9wA-3qy9A:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		4 / 5 THR A 203
GLU A 194
THR A 132
HIS A 182
 None
 1.41A 3n58A-3qy9A:
6.6		 3n58A-3qy9A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		5 / 12 GLU A  20
ALA A  16
ASP A  53
ALA A  52
VAL A  27
 None
 1.15A 3nvkF-3qy9A:
undetectable
3nvkJ-3qy9A:
3.2		 3nvkF-3qy9A:
22.34
3nvkJ-3qy9A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3qy9 DIHYDRODIPICOLINATE
REDUCTASE
(Staphylococcus
aureus) 		5 / 12 VAL A  49
LEU A  64
ILE A   6
LEU A   4
LEU A  94
 None
 1.11A 4y0qA-3qy9A:
undetectable		 4y0qA-3qy9A:
22.59