SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 114
LEU A  48
LEU A  31
GLY A 102
ALA A  56
 None
 1.07A 1b02A-3qyjA:
undetectable		 1b02A-3qyjA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 TYR A  34
HIS A  32
PRO A 168
VAL A 203
 None
 1.39A 1q13A-3qyjA:
undetectable		 1q13A-3qyjA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 LEU A  31
LEU A  28
MET A  90
 None
 0.82A 1ya3B-3qyjA:
undetectable		 1ya3B-3qyjA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 5 ALA A 214
TRP A 150
LEU A 153
ALA A 215
 None
 1.15A 2jstA-3qyjA:
undetectable
2jstB-3qyjA:
undetectable		 2jstA-3qyjA:
10.54
2jstB-3qyjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ASP A 218
ASN A  76
ASP A 104
ILE A 129
ASP A 210
 None
 1.49A 2qmjA-3qyjA:
undetectable		 2qmjA-3qyjA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 PHE A 271
TYR A  34
LEU A 237
 None
 0.73A 3keeB-3qyjA:
undetectable		 3keeB-3qyjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 4 PHE A 271
TYR A  34
VAL A 236
LEU A 237
 None
 1.32A 3keeD-3qyjA:
undetectable		 3keeD-3qyjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 ARG A 196
ARG A  67
ASP A  58
 None
 1.00A 3wipG-3qyjA:
undetectable
3wipH-3qyjA:
undetectable		 3wipG-3qyjA:
20.82
3wipH-3qyjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 PHE A 183
GLU A 240
ASP A 104
ASP A 128
GLY A 269
 None
 1.33A 4qb9F-3qyjA:
undetectable		 4qb9F-3qyjA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 237
ASN A 286
THR A 289
VAL A 101
ALA A 125
 None
 1.11A 4x1iB-3qyjA:
undetectable		 4x1iB-3qyjA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 LYS A  79
ARG A 105
ASP A 210
TYR A 136
 None
 1.47A 5a06A-3qyjA:
4.1		 5a06A-3qyjA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 LYS A  79
ARG A 105
ASP A 210
TYR A 136
 None
 1.46A 5a06C-3qyjA:
4.1		 5a06C-3qyjA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 LYS A  79
ARG A 105
ASP A 210
TYR A 136
 None
 1.43A 5a06D-3qyjA:
4.1		 5a06D-3qyjA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 LYS A  79
ARG A 105
ASP A 210
TYR A 136
 None
 1.46A 5a06E-3qyjA:
4.4		 5a06E-3qyjA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 LYS A  79
ARG A 105
ASP A 210
TYR A 136
 None
 1.44A 5a06F-3qyjA:
3.9		 5a06F-3qyjA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 5 LEU A  28
PHE A  98
LEU A 288
PHE A 287
 None
 1.19A 5x1fC-3qyjA:
undetectable
5x1fJ-3qyjA:
undetectable		 5x1fC-3qyjA:
22.86
5x1fJ-3qyjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 5 ILE A 204
PHE A 198
TYR A  34
ARG A 105
 None
 1.28A 5z84N-3qyjA:
undetectable
5z84W-3qyjA:
undetectable		 5z84N-3qyjA:
18.74
5z84W-3qyjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_B_Y70B502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 3qyj ALR0039 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 PRO A 273
HIS A 103
GLU A 274
PHE A   5
GLN A  36
 None
 1.43A 6h0gB-3qyjA:
0.0
6h0gC-3qyjA:
undetectable		 6h0gB-3qyjA:
14.06
6h0gC-3qyjA:
8.53