SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qyn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 3qyn TUMOR PROTEIN 63
(Homo
sapiens) 		5 / 10 LEU A 288
ALA A 188
VAL A 263
ILE A 174
VAL A 140
 None
 0.97A 2nnjA-3qynA:
undetectable		 2nnjA-3qynA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3qyn TUMOR PROTEIN 63
(Homo
sapiens) 		3 / 3 CYH A 306
PRO A 281
ASP A 316
 None
 0.95A 3hlwB-3qynA:
undetectable		 3hlwB-3qynA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3qyn TUMOR PROTEIN 63
(Homo
sapiens) 		3 / 3 ARG A 227
THR A 262
THR A 152
 None
 0.81A 3k2hB-3qynA:
undetectable		 3k2hB-3qynA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 3qyn TUMOR PROTEIN 63
(Homo
sapiens) 		4 / 7 THR A 157
ARG A 313
PHE A 142
SER A 145
 None
 1.44A 4o4dA-3qynA:
undetectable		 4o4dA-3qynA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3qyn TUMOR PROTEIN 63
(Homo
sapiens) 		3 / 3 CYH A 306
PRO A 281
ASP A 316
 None
 0.93A 4pm5A-3qynA:
undetectable		 4pm5A-3qynA:
20.45