SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 3qyr ECHA16_2
(Mycobacterium
avium) 		4 / 5 CYH A  62
PRO A  59
THR A 123
THR A 100
 None
 1.13A 1ymxB-3qyrA:
undetectable		 1ymxB-3qyrA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3qyr ECHA16_2
(Mycobacterium
avium) 		4 / 5 LEU A 168
ALA A 114
ILE A  94
LYS A 142
 None
 0.99A 2othA-3qyrA:
undetectable		 2othA-3qyrA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3qyr ECHA16_2
(Mycobacterium
avium) 		4 / 5 VAL A  14
VAL A  49
THR A  16
ARG A  15
 None
 1.16A 3bjwA-3qyrA:
undetectable		 3bjwA-3qyrA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3qyr ECHA16_2
(Mycobacterium
avium) 		4 / 5 VAL A  14
VAL A  49
THR A  16
ARG A  15
 None
 1.20A 3bjwC-3qyrA:
undetectable		 3bjwC-3qyrA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 12 ASN A  95
ILE A  94
GLY A  64
ALA A  27
GLY A  56
 None
 0.81A 3hs6B-3qyrA:
undetectable		 3hs6B-3qyrA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 12 ASN A  95
ILE A  94
GLY A  64
ALA A  27
GLY A  56
 None
 0.88A 4e1gA-3qyrA:
undetectable		 4e1gA-3qyrA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3qyr ECHA16_2
(Mycobacterium
avium) 		3 / 3 PHE A  36
ASP A  34
ARG A  82
 None
 0.89A 4eahF-3qyrA:
undetectable		 4eahF-3qyrA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3qyr ECHA16_2
(Mycobacterium
avium) 		3 / 3 PHE A  36
ASP A  34
ARG A  82
 None
 0.88A 4eahG-3qyrA:
undetectable		 4eahG-3qyrA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3qyr ECHA16_2
(Mycobacterium
avium) 		4 / 4 LEU A 168
ALA A 114
ILE A  94
LYS A 142
 None
 1.09A 4eixA-3qyrA:
undetectable		 4eixA-3qyrA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 12 ALA A  97
GLY A 102
ILE A  53
GLY A  56
PHE A  61
 None
 1.09A 4r29D-3qyrA:
undetectable		 4r29D-3qyrA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 12 ASP A 110
VAL A  90
VAL A  52
LEU A  40
ALA A  41
 None
 1.33A 4yhaA-3qyrA:
undetectable		 4yhaA-3qyrA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 12 GLU A 171
ILE A 113
LEU A 179
GLY A 180
ILE A  53
 None
 1.00A 5j7wD-3qyrA:
undetectable		 5j7wD-3qyrA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 10 PHE A  36
PHE A  37
TRP A  83
GLY A 102
GLY A 101
 None
None
None
None
EDO  A 250 ( 4.2A)
 1.49A 5lbtA-3qyrA:
undetectable
5lbtB-3qyrA:
undetectable		 5lbtA-3qyrA:
20.82
5lbtB-3qyrA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3qyr ECHA16_2
(Mycobacterium
avium) 		5 / 12 GLU A 171
VAL A 172
LEU A 107
ALA A 163
GLY A  96
 None
 1.08A 5syeB-3qyrA:
undetectable		 5syeB-3qyrA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 3qyr ECHA16_2
(Mycobacterium
avium) 		3 / 3 TYR A 108
PRO A  84
LEU A  40
 None
 0.86A 6beoA-3qyrA:
undetectable		 6beoA-3qyrA:
2.70