SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AL4_A_DVAA6_0
(GRAMICIDIN D)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 5 ALA A 159
VAL A 157
TRP A 209
TRP A 165
 None
 1.43A 1al4A-3qyyA:
undetectable
1al4B-3qyyA:
undetectable		 1al4A-3qyyA:
13.25
1al4B-3qyyA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 8 ALA A 275
LEU A 287
GLU A 260
THR A 230
 None
 0.82A 1ie4B-3qyyA:
undetectable
1ie4D-3qyyA:
undetectable		 1ie4B-3qyyA:
19.64
1ie4D-3qyyA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		5 / 11 LEU A 196
ALA A 254
VAL A 192
MET A 174
LEU A 177
 None
None
None
None
C2E  A 487 (-4.1A)
 1.42A 1kt6A-3qyyA:
undetectable		 1kt6A-3qyyA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		5 / 11 LEU A 196
ALA A 254
VAL A 192
MET A 174
LEU A 177
 None
None
None
None
C2E  A 487 (-4.1A)
 1.39A 1kt7A-3qyyA:
undetectable		 1kt7A-3qyyA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_E_SAME500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		5 / 11 SER A 253
GLY A 255
SER A 256
ASN A 234
ASP A 175
 None
 0.98A 2c2bE-3qyyA:
undetectable
2c2bF-3qyyA:
undetectable		 2c2bE-3qyyA:
16.52
2c2bF-3qyyA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 8 ARG A 146
GLY A 214
ARG A 212
THR A 141
 None
None
C2E  A 487 (-3.1A)
None
 0.92A 2f9wA-3qyyA:
undetectable
2f9wB-3qyyA:
undetectable		 2f9wA-3qyyA:
22.66
2f9wB-3qyyA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 6 ASP A 175
SER A 253
SER A 282
GLY A 283
 None
 1.02A 2j2pA-3qyyA:
undetectable
2j2pC-3qyyA:
undetectable		 2j2pA-3qyyA:
23.11
2j2pC-3qyyA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 5 LEU A 196
LEU A 193
LEU A 187
MET A 174
 None
 0.98A 2oaxF-3qyyA:
undetectable		 2oaxF-3qyyA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 7 CYH A 149
TRP A 209
LEU A 204
ILE A 210
 None
 0.87A 2q83A-3qyyA:
undetectable		 2q83A-3qyyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 6 GLU A 260
ILE A 263
GLU A 267
ALA A 257
 None
 1.00A 3pgyA-3qyyA:
undetectable
3pgyB-3qyyA:
undetectable		 3pgyA-3qyyA:
18.18
3pgyB-3qyyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3qyy RESPONSE REGULATOR
(Xanthomonas
campestris) 		4 / 8 TYR A 201
LEU A 144
ALA A 152
SER A 156
 None
 0.94A 3rodA-3qyyA:
undetectable		 3rodA-3qyyA:
21.63