SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		3 / 3 ALA A  81
VAL A  87
TRP A  86
 None
 0.93A 1c4dA-3qz1A:
undetectable
1c4dB-3qz1A:
undetectable		 1c4dA-3qz1A:
6.28
1c4dB-3qz1A:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		3 / 3 ALA A 419
VAL A 357
TRP A 301
 HEM  A 500 (-4.3A)
HEM  A 500 ( 4.5A)
None
 0.90A 1tkqB-3qz1A:
undetectable		 1tkqB-3qz1A:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		3 / 3 LEU A 428
LEU A 129
MET A 255
 HEM  A 500 (-3.8A)
None
None
 0.51A 1ya3B-3qz1A:
undetectable		 1ya3B-3qz1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		3 / 3 TRP A 117
LEU A 110
LYS A  99
 HEM  A 500 (-4.4A)
3QZ  A 501 (-4.3A)
None
 1.39A 1yajK-3qz1A:
undetectable		 1yajK-3qz1A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 11 ALA A 296
VAL A 440
GLY A 291
ILE A 172
VAL A 140
 None
None
HEM  A 500 (-3.6A)
None
None
 1.32A 2uxpB-3qz1A:
undetectable		 2uxpB-3qz1A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 11 LEU A  49
ASN A 386
LEU A  72
VAL A 382
MET A 381
 None
 1.11A 2ylqA-3qz1A:
2.7		 2ylqA-3qz1A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		4 / 5 VAL A 440
VAL A 439
THR A 295
ARG A 443
 None
None
HEM  A 500 (-3.3A)
None
 0.71A 3bjwA-3qz1A:
undetectable		 3bjwA-3qz1A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		4 / 5 VAL A 440
VAL A 439
THR A 295
ARG A 443
 None
None
HEM  A 500 (-3.3A)
None
 0.78A 3bjwC-3qz1A:
undetectable		 3bjwC-3qz1A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 LEU A  49
ASN A 386
LEU A  72
VAL A 382
MET A 381
 None
 1.09A 3zqtA-3qz1A:
2.3		 3zqtA-3qz1A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		4 / 7 ASP A 286
LEU A 176
GLN A 239
LEU A 240
 3QZ  A 501 ( 4.7A)
None
None
None
 1.12A 4ib4A-3qz1A:
undetectable		 4ib4A-3qz1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 LEU A 441
LEU A 444
LEU A 306
ILE A 348
LEU A 341
 None
 1.13A 4j24A-3qz1A:
undetectable		 4j24A-3qz1A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		3 / 3 TRP A 200
GLN A 227
THR A 199
 3QZ  A 501 (-4.1A)
None
None
 0.98A 4m2xA-3qz1A:
undetectable		 4m2xA-3qz1A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 LEU A 176
GLY A 179
MET A 259
ILE A 289
PHE A 189
 None
 1.25A 4p6xI-3qz1A:
2.3		 4p6xI-3qz1A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 10 LEU A 428
LEU A 287
VAL A 280
LEU A 240
LEU A 260
 HEM  A 500 (-3.8A)
None
None
None
None
 1.09A 4po0A-3qz1A:
undetectable		 4po0A-3qz1A:
21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		6 / 12 VAL A 101
ASP A 107
SER A 109
ARG A 232
VAL A 358
LEU A 362
 None
None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-3.8A)
HEM  A 500 (-4.3A)
HEM  A 500 (-4.7A)
 0.98A 4y8wA-3qz1A:
52.3		 4y8wA-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		7 / 12 VAL A 101
SER A 109
TRP A 200
ARG A 232
ASP A 286
VAL A 358
LEU A 362
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.1A)
3QZ  A 501 (-3.8A)
3QZ  A 501 ( 4.7A)
HEM  A 500 (-4.3A)
HEM  A 500 (-4.7A)
 0.78A 4y8wA-3qz1A:
52.3		 4y8wA-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 VAL A 101
SER A 109
TRP A 200
ASP A 286
GLY A 290
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.1A)
3QZ  A 501 ( 4.7A)
3QZ  A 501 (-3.9A)
 1.06A 4y8wA-3qz1A:
52.3		 4y8wA-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		6 / 12 VAL A 101
ASP A 107
SER A 109
ARG A 232
VAL A 358
LEU A 362
 None
None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-3.8A)
HEM  A 500 (-4.3A)
HEM  A 500 (-4.7A)
 0.97A 4y8wB-3qz1A:
52.1		 4y8wB-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 VAL A 101
SER A 109
ASP A 286
GLY A 290
VAL A 469
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 ( 4.7A)
3QZ  A 501 (-3.9A)
None
 1.11A 4y8wB-3qz1A:
52.1		 4y8wB-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		7 / 12 VAL A 101
SER A 109
TRP A 200
ARG A 232
ASP A 286
VAL A 358
LEU A 362
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.1A)
3QZ  A 501 (-3.8A)
3QZ  A 501 ( 4.7A)
HEM  A 500 (-4.3A)
HEM  A 500 (-4.7A)
 0.72A 4y8wB-3qz1A:
52.1		 4y8wB-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 VAL A 101
SER A 109
TRP A 200
ASP A 286
GLY A 290
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.1A)
3QZ  A 501 ( 4.7A)
3QZ  A 501 (-3.9A)
 1.03A 4y8wB-3qz1A:
52.1		 4y8wB-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		6 / 12 VAL A 101
ASP A 107
SER A 109
ARG A 232
VAL A 358
LEU A 362
 None
None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-3.8A)
HEM  A 500 (-4.3A)
HEM  A 500 (-4.7A)
 0.95A 4y8wC-3qz1A:
52.0		 4y8wC-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 VAL A 101
SER A 109
LEU A 110
GLY A 290
VAL A 469
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.3A)
3QZ  A 501 (-3.9A)
None
 1.03A 4y8wC-3qz1A:
52.0		 4y8wC-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		8 / 12 VAL A 101
SER A 109
LEU A 110
TRP A 200
ILE A 229
ARG A 232
VAL A 358
LEU A 362
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.3A)
3QZ  A 501 (-4.1A)
None
3QZ  A 501 (-3.8A)
HEM  A 500 (-4.3A)
HEM  A 500 (-4.7A)
 0.91A 4y8wC-3qz1A:
52.0		 4y8wC-3qz1A:
75.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		6 / 12 VAL A 101
SER A 109
LEU A 110
TRP A 200
ILE A 229
GLY A 290
 None
3QZ  A 501 (-3.8A)
3QZ  A 501 (-4.3A)
3QZ  A 501 (-4.1A)
None
3QZ  A 501 (-3.9A)
 1.18A 4y8wC-3qz1A:
52.0		 4y8wC-3qz1A:
75.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		5 / 12 ALA A  81
GLN A  94
PHE A  89
GLY A  91
TYR A 113
 None
 1.26A 5hfjB-3qz1A:
undetectable		 5hfjB-3qz1A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		4 / 5 MET A 282
SER A 283
VAL A 280
GLY A 278
 None
 1.09A 5k50A-3qz1A:
undetectable		 5k50A-3qz1A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_C_ACTC1403_0
(L-THREONINE
3-DEHYDROGENASE)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		4 / 4 MET A 282
SER A 283
VAL A 280
GLY A 278
 None
 1.04A 5k50C-3qz1A:
undetectable		 5k50C-3qz1A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3qz1 STEROID
21-HYDROXYLASE
(Bos
taurus) 		4 / 6 PRO A  58
GLY A  57
THR A  53
LYS A  55
 None
 1.13A 5xxiA-3qz1A:
40.4		 5xxiA-3qz1A:
29.49