SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3qz3 FERRITIN
(Vibrio
cholerae) 		4 / 8 ALA A  11
LEU A   8
ALA A 114
THR A 122
 None
 0.79A 1ie4B-3qz3A:
undetectable
1ie4D-3qz3A:
undetectable		 1ie4B-3qz3A:
18.18
1ie4D-3qz3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 11 PHE A  48
ILE A 143
LEU A  89
GLY A  90
ALA A 156
 EDO  A 182 ( 4.7A)
None
None
None
None
 1.36A 1ju6A-3qz3A:
undetectable		 1ju6A-3qz3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 11 PHE A  48
ILE A 143
LEU A  89
GLY A  90
ALA A 156
 EDO  A 182 ( 4.7A)
None
None
None
None
 1.36A 1ju6D-3qz3A:
undetectable		 1ju6D-3qz3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 12 PHE A  86
LEU A 144
LEU A  29
LEU A  49
TYR A  30
 None
 1.31A 3adsA-3qz3A:
undetectable		 3adsA-3qz3A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		3 / 3 GLN A 118
THR A 116
LEU A   8
 None
 0.76A 3ondA-3qz3A:
undetectable		 3ondA-3qz3A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		3 / 3 GLN A 118
THR A 116
LEU A   8
 None
 0.76A 3ondB-3qz3A:
undetectable		 3ondB-3qz3A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 12 ILE A 143
LEU A  89
GLY A  90
ILE A 160
ALA A 156
 None
 0.86A 3uwlB-3qz3A:
undetectable		 3uwlB-3qz3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 11 PHE A  48
ILE A 143
LEU A  89
GLY A  90
ALA A 156
 EDO  A 182 ( 4.7A)
None
None
None
None
 1.32A 5fctA-3qz3A:
undetectable		 5fctA-3qz3A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 12 ILE A 143
LEU A  89
GLY A  90
ILE A 160
ALA A 156
 None
 0.86A 5j7wD-3qz3A:
undetectable		 5j7wD-3qz3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3qz3 FERRITIN
(Vibrio
cholerae) 		4 / 6 TYR A  30
GLN A  58
GLU A 136
THR A  96
 None
None
EDO  A 182 ( 4.9A)
None
 1.30A 6djzA-3qz3A:
undetectable		 6djzA-3qz3A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3qz3 FERRITIN
(Vibrio
cholerae) 		5 / 11 PHE A  48
ILE A 143
LEU A  89
GLY A  90
ALA A 156
 EDO  A 182 ( 4.7A)
None
None
None
None
 1.35A 6r2eF-3qz3A:
undetectable		 6r2eF-3qz3A:
19.20