SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qzy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 LEU A  22
LEU A 116
LEU A  94
LEU A  92
 None
 0.91A 1errA-3qzyA:
undetectable		 1errA-3qzyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 LEU A 132
LEU A 139
ILE A 178
GLU A 183
 None
 1.02A 1mt1A-3qzyA:
undetectable
1mt1F-3qzyA:
undetectable		 1mt1A-3qzyA:
10.82
1mt1F-3qzyA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 ILE A 178
GLU A 183
LEU A 132
LEU A 139
 None
 0.90A 1mt1B-3qzyA:
undetectable
1mt1C-3qzyA:
undetectable		 1mt1B-3qzyA:
18.15
1mt1C-3qzyA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 ASN A 226
ILE A 169
MET A 113
 FAD  A 334 (-2.9A)
None
FAD  A 334 ( 3.7A)
 0.68A 2h42C-3qzyA:
undetectable		 2h42C-3qzyA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 LEU A 212
LEU A 216
LEU A 118
MET A 142
 None
 0.92A 2oaxF-3qzyA:
undetectable		 2oaxF-3qzyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 HIS A 225
TYR A 252
ASP A 111
ARG A  10
 FAD  A 334 (-3.5A)
FAD  A 334 (-4.2A)
None
FAD  A 334 (-2.9A)
 0.90A 2v57A-3qzyA:
1.0		 2v57A-3qzyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 HIS A 225
TYR A 252
ASP A 111
ARG A  10
 FAD  A 334 (-3.5A)
FAD  A 334 (-4.2A)
None
FAD  A 334 (-2.9A)
 0.89A 2v57C-3qzyA:
undetectable		 2v57C-3qzyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 PRO A   3
THR A 112
ILE A 119
ASP A 121
PHE A 115
 None
None
None
None
IMD  A 261 (-4.5A)
 1.29A 2v95A-3qzyA:
undetectable		 2v95A-3qzyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 GLU A 177
LEU A 180
ASP A 181
 None
 0.47A 3ko0A-3qzyA:
1.7		 3ko0A-3qzyA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 GLU A 177
LEU A 180
ASP A 181
 None
 0.34A 3ko0T-3qzyA:
1.8		 3ko0T-3qzyA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_B_ACTB601_0
(CHOLINE OXIDASE)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TRP A 110
HIS A 227
VAL A 165
HIS A 161
 FAD  A 334 (-3.4A)
None
None
FAD  A 334 (-4.1A)
 1.45A 3nneB-3qzyA:
0.7		 3nneB-3qzyA:
16.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P0K_A_ACTA267_0
(SULFHYDRYL OXIDASE)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 5 VAL A 149
ARG A 159
TYR A 162
MET A 163
LYS A 166
 None
None
FAD  A 334 ( 4.2A)
None
None
 0.61A 3p0kA-3qzyA:
33.3		 3p0kA-3qzyA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 SER A  29
THR A  35
THR A  32
PRO A  74
 None
 1.02A 5jhdE-3qzyA:
undetectable
5jhdG-3qzyA:
undetectable		 5jhdE-3qzyA:
24.39
5jhdG-3qzyA:
19.03