SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r03'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3r03 NUDIX HYDROLASE
(Rhodospirillum
rubrum) 		4 / 8 GLU A  60
GLU A  72
GLU A  76
GLU A  75
 None
 1.10A 1knyA-3r03A:
undetectable
1knyB-3r03A:
undetectable		 1knyA-3r03A:
21.60
1knyB-3r03A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3r03 NUDIX HYDROLASE
(Rhodospirillum
rubrum) 		4 / 6 VAL A 126
LEU A  39
PHE A  54
MET A 136
 None
 1.10A 1x8vA-3r03A:
undetectable		 1x8vA-3r03A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3r03 NUDIX HYDROLASE
(Rhodospirillum
rubrum) 		4 / 7 ILE A  22
HIS A  94
ALA A  92
HIS A 100
 None
 0.95A 5hrqE-3r03A:
undetectable
5hrqF-3r03A:
undetectable
5hrqJ-3r03A:
undetectable		 5hrqE-3r03A:
9.02
5hrqF-3r03A:
10.42
5hrqJ-3r03A:
10.42