SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r08'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
(Cricetulus
migratorius) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 213
 None
 1.45A 1a7yA-3r08H:
undetectable
1a7yC-3r08H:
undetectable		 1a7yA-3r08H:
12.90
1a7yC-3r08H:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		5 / 12 VAL L 163
LEU L 175
VAL L 136
THR L 200
ARG L 108
 None
 1.01A 2cbrA-3r08L:
undetectable		 2cbrA-3r08L:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3r08 T-CELL SURFACE
GLYCOPROTEIN CD3
EPSILON CHAIN
MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
(Cricetulus
migratorius;
Cricetulus
migratorius) 		4 / 4 SER E  25
SER H  53
THR H  52
SER H  52
 None
 1.47A 3loqA-3r08E:
undetectable		 3loqA-3r08E:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.02A 3tgvB-3r08L:
undetectable		 3tgvB-3r08L:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
T-CELL SURFACE
GLYCOPROTEIN CD3
EPSILON CHAIN
(Cricetulus
migratorius) 		4 / 7 TYR L  32
TYR E  59
PRO E  22
TYR E   8
 None
 1.11A 3ugrA-3r08L:
undetectable		 3ugrA-3r08L:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 7 VAL L 150
TYR L 192
LEU L 181
ASP L 185
 None
 1.25A 4hxyB-3r08L:
undetectable		 4hxyB-3r08L:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius;
Cricetulus
migratorius) 		3 / 3 ASP L   1
ARG H  66
ARG H  38
 None
 0.82A 4x5iA-3r08L:
undetectable		 4x5iA-3r08L:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius;
Cricetulus
migratorius) 		3 / 3 ASP L   1
ARG H  66
ARG H  38
 None
 0.93A 5eajB-3r08L:
undetectable		 5eajB-3r08L:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
(Cricetulus
migratorius) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.81A 5ecoD-3r08H:
undetectable		 5ecoD-3r08H:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 7 GLY L  66
ILE L  29
GLN L  89
TYR L  50
 None
 1.05A 5vlmC-3r08L:
undetectable		 5vlmC-3r08L:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_1
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3r08 T-CELL SURFACE
GLYCOPROTEIN CD3
EPSILON CHAIN
MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
(Cricetulus
migratorius;
Cricetulus
migratorius) 		4 / 4 SER H  52
ASP E  43
HIS E  45
ASP E  26
 None
 1.47A 5x7fA-3r08H:
0.0		 5x7fA-3r08H:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
(Cricetulus
migratorius) 		3 / 3 SER H 216
ALA H 211
VAL H 210
 None
 0.50A 5xiwC-3r08H:
undetectable		 5xiwC-3r08H:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		5 / 10 TYR L  86
ILE L  21
LEU L  46
LEU L  54
GLU L  79
 None
 1.20A 5y7pG-3r08L:
undetectable		 5y7pG-3r08L:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		3 / 3 LYS L 142
PRO L 141
LYS L 107
 None
 0.87A 5y9yA-3r08L:
undetectable		 5y9yA-3r08L:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN
(Cricetulus
migratorius) 		5 / 12 LEU L 175
ASN L 137
PHE L 139
ASP L 170
ASP L 165
 None
 1.44A 6dwnB-3r08L:
undetectable		 6dwnB-3r08L:
16.98