SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		3 / 3 ASP A 627
PHE A 583
ARG A 662
 None
 0.90A 2a3aA-3r0hA:
undetectable		 2a3aA-3r0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		4 / 7 PHE A 642
TYR A 521
PRO A 601
THR A 607
 DTT  A   5 ( 3.3A)
None
None
None
 1.20A 2q6kA-3r0hA:
undetectable		 2q6kA-3r0hA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		5 / 12 THR A 518
GLY A 626
ALA A 609
VAL A 511
VAL A 660
 None
 1.01A 2yvlD-3r0hA:
undetectable		 2yvlD-3r0hA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		4 / 7 ILE A 541
ILE A 546
VAL A 556
LEU A 559
 None
 0.61A 3r9vA-3r0hA:
undetectable
3r9vB-3r0hA:
undetectable		 3r9vA-3r0hA:
23.16
3r9vB-3r0hA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		4 / 7 PHE A 583
VAL A 585
ILE A 619
GLU A 581
 None
 1.09A 4a97H-3r0hA:
undetectable		 4a97H-3r0hA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		3 / 3 TYR A 616
LYS A 590
LYS A 593
 None
 1.11A 5dbyA-3r0hA:
undetectable		 5dbyA-3r0hA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3r0h INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN
(Drosophila
melanogaster) 		4 / 6 PHE A 560
ILE A 517
ASP A 627
GLY A 626
 None
 0.99A 5x5qE-3r0hA:
undetectable		 5x5qE-3r0hA:
21.07