SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 7 TYR A  19
ILE A  35
PRO A 114
GLU A 120
 None
 0.53A 1oniA-3r0pA:
23.4
1oniB-3r0pA:
23.2		 1oniA-3r0pA:
43.18
1oniB-3r0pA:
43.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 6 TYR A  19
ILE A  35
PRO A 114
GLU A 120
 None
 0.49A 1oniB-3r0pA:
23.2
1oniC-3r0pA:
23.4		 1oniB-3r0pA:
43.18
1oniC-3r0pA:
43.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 6 TYR A  19
ILE A  35
PRO A 114
GLU A 120
 None
 0.34A 1oniA-3r0pA:
23.4
1oniC-3r0pA:
23.4		 1oniA-3r0pA:
43.18
1oniC-3r0pA:
43.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 7 TYR A  19
ILE A  35
PRO A 114
GLU A 120
 None
 0.52A 1oniD-3r0pA:
23.6
1oniE-3r0pA:
23.6		 1oniD-3r0pA:
43.18
1oniE-3r0pA:
43.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 7 TYR A  19
ILE A  35
PRO A 114
GLU A 120
 None
 0.57A 1oniG-3r0pA:
23.3
1oniI-3r0pA:
23.4		 1oniG-3r0pA:
43.18
1oniI-3r0pA:
43.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 7 PHE A  98
VAL A  56
VAL A  90
VAL A  93
 None
 1.00A 2qbnA-3r0pA:
undetectable		 2qbnA-3r0pA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		3 / 3 ALA A  62
VAL A  63
GLN A  21
 None
 0.70A 3of4B-3r0pA:
undetectable		 3of4B-3r0pA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		5 / 12 SER A   9
TYR A  19
ALA A  22
SER A  32
LEU A  31
 None
 1.10A 4coxA-3r0pA:
undetectable		 4coxA-3r0pA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		5 / 12 SER A   9
TYR A  19
ALA A  22
SER A  32
LEU A  31
 None
 1.10A 4coxC-3r0pA:
undetectable		 4coxC-3r0pA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 5 GLN A  52
HIS A  54
ILE A 119
ILE A  89
 None
 1.24A 5dnuA-3r0pA:
undetectable		 5dnuA-3r0pA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE
(uncultured
organism) 		4 / 5 GLN A  52
HIS A  54
ILE A 119
ILE A  89
 None
 1.27A 5dnvA-3r0pA:
undetectable		 5dnvA-3r0pA:
19.06