SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 GLN C 305
HIS C  67
PRO C 303
 None
 0.78A 1d8cA-3r0qC:
undetectable		 1d8cA-3r0qC:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 SER C  81
GLY C  80
ARG C  54
 SAH  C   1 ( 4.4A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-2.7A)
 0.56A 1t9wA-3r0qC:
undetectable		 1t9wA-3r0qC:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.48A 2gluA-3r0qC:
10.4		 2gluA-3r0qC:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 6 ARG C  54
ASP C  76
SER C  81
GLY C  82
 SAH  C   1 (-2.7A)
SAH  C   1 ( 4.5A)
SAH  C   1 ( 4.4A)
None
 0.88A 2j2pA-3r0qC:
undetectable
2j2pC-3r0qC:
undetectable		 2j2pA-3r0qC:
20.32
2j2pC-3r0qC:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 6 ARG C  54
ASP C  76
SER C  81
GLY C  82
 SAH  C   1 (-2.7A)
SAH  C   1 ( 4.5A)
SAH  C   1 ( 4.4A)
None
 0.85A 2j2pD-3r0qC:
undetectable
2j2pF-3r0qC:
undetectable		 2j2pD-3r0qC:
20.32
2j2pF-3r0qC:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 7 ILE C 328
PRO C 314
GLY C 290
TRP C 291
 None
 1.23A 2pnjB-3r0qC:
undetectable		 2pnjB-3r0qC:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 VAL C 294
TRP C 291
TRP C 180
 None
 1.27A 2xdcC-3r0qC:
undetectable
2xdcD-3r0qC:
undetectable		 2xdcC-3r0qC:
5.67
2xdcD-3r0qC:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 11 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.46A 3g88A-3r0qC:
8.6		 3g88A-3r0qC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 11 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.45A 3g88B-3r0qC:
8.5		 3g88B-3r0qC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.42A 3g89A-3r0qC:
8.2		 3g89A-3r0qC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 11 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.44A 3g89B-3r0qC:
8.6		 3g89B-3r0qC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.46A 3g8bA-3r0qC:
8.6		 3g8bA-3r0qC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 GLY C  78
GLY C  80
ALA C 101
THR C 102
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-3.4A)
SAH  C   1 (-4.5A)
SAH  C   1 (-3.4A)
 0.47A 3g8bB-3r0qC:
8.3		 3g8bB-3r0qC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 7 ALA C 182
PRO C 251
ARG C 178
ALA C 313
 None
 1.13A 3twpC-3r0qC:
undetectable		 3twpC-3r0qC:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 LEU C  42
GLY C  80
ILE C  83
HIS C 107
LEU C 111
 None
SAH  C   1 ( 3.7A)
SAH  C   1 (-4.7A)
None
None
 1.04A 3uj6A-3r0qC:
9.1		 3uj6A-3r0qC:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 6 GLY C  80
GLU C 100
ASP C  76
GLU C 129
 SAH  C   1 ( 3.7A)
SAH  C   1 (-3.0A)
SAH  C   1 ( 4.5A)
SAH  C   1 (-3.4A)
 0.77A 3vywC-3r0qC:
6.0		 3vywC-3r0qC:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 VAL C 294
TRP C 291
TRP C 180
 None
 1.30A 3zq8A-3r0qC:
undetectable
3zq8B-3r0qC:
undetectable		 3zq8A-3r0qC:
5.67
3zq8B-3r0qC:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 TRP C 291
VAL C 294
TRP C 180
 None
 1.19A 3zq8A-3r0qC:
undetectable
3zq8B-3r0qC:
undetectable		 3zq8A-3r0qC:
5.67
3zq8B-3r0qC:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 5 LEU C 181
ILE C 359
MET C 347
PHE C 327
 None
 1.08A 4dc3B-3r0qC:
3.1		 4dc3B-3r0qC:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 ASP C  76
TRP C 322
SER C  81
 SAH  C   1 ( 4.5A)
None
SAH  C   1 ( 4.4A)
 1.06A 4lrhA-3r0qC:
undetectable		 4lrhA-3r0qC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		3 / 3 PHE C 376
THR C 252
LEU C 285
 None
 0.72A 4qztA-3r0qC:
undetectable		 4qztA-3r0qC:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 5 LYS C 255
ILE C 267
PHE C 155
VAL C 264
 None
 1.32A 4tvtA-3r0qC:
undetectable		 4tvtA-3r0qC:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 GLY C  78
GLY C  80
LEU C  84
ALA C 101
GLU C 129
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-4.2A)
SAH  C   1 (-3.4A)
SAH  C   1 (-3.4A)
 0.98A 5c0oE-3r0qC:
9.5		 5c0oE-3r0qC:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		5 / 12 GLU C 100
GLY C  80
ILE C  83
ALA C  85
ALA C 108
 SAH  C   1 (-3.0A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-4.7A)
None
None
 1.18A 5kvaB-3r0qC:
8.3		 5kvaB-3r0qC:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2
(Arabidopsis
thaliana) 		4 / 5 TYR C 173
SER C 297
ALA C 304
GLN C  64
 None
 1.38A 5n0tA-3r0qC:
undetectable		 5n0tA-3r0qC:
22.00