SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IGX_A_EPAA700_1 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	3r0r	PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN (Porcine circovirus 2)	5 / 12	PHE A 100 PHE A 197 SER A 116 GLY A 194 LEU A 193	None	0.97A	1igxA-3r0rA: undetectable	1igxA-3r0rA: 16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_A_DVAA6_0 (MINI-GRAMICIDIN A)	3r0r	PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN (Porcine circovirus 2)	3 / 3	ALA A 117 VAL A 137 TRP A 62	None	1.00A	1tkqA-3r0rA: undetectable	1tkqA-3r0rA: 7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	3r0r	PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN (Porcine circovirus 2)	3 / 3	ASP A 122 PHE A 124 ARG A 68	None	0.91A	2a3aA-3r0rA: undetectable	2a3aA-3r0rA: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_ACTA1181_0 (WNT INHIBITORY FACTOR 1)	3r0r	PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN (Porcine circovirus 2)	3 / 3	TYR A 136 VAL A 125 THR A 195	None	0.61A	2ygnA-3r0rA: undetectable	2ygnA-3r0rA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_A_SAMA401_1 (METHYLTRANSFERASE NSUN4)	3r0r	PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN (Porcine circovirus 2)	3 / 3	ASP A 122 ARG A 68 ASP A 163	None	0.73A	4fp9A-3r0rA: undetectable	4fp9A-3r0rA: 20.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IGX_A_EPAA700_1","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","3r0r","PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN","Porcine circovirus 2",5,"PHE A 100;PHE A 197;SER A 116;GLY A 194;LEU A 193","None","0.97A","1igxA-3r0rA:undetectable","1igxA-3r0rA:16.61"],["1TKQ_A_DVAA6_0","MINI-GRAMICIDIN A","3r0r","PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN","Porcine circovirus 2",3,"ALA A 117;VAL A 137;TRP A  62","None","1.00A","1tkqA-3r0rA:undetectable","1tkqA-3r0rA:7.44"],["2A3A_A_TEPA1436_1","CHITINASE","3r0r","PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN","Porcine circovirus 2",3,"ASP A 122;PHE A 124;ARG A  68","None","0.91A","2a3aA-3r0rA:undetectable","2a3aA-3r0rA:17.80"],["2YGN_A_ACTA1181_0","WNT INHIBITORY FACTOR 1","3r0r","PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN","Porcine circovirus 2",3,"TYR A 136;VAL A 125;THR A 195","None","0.61A","2ygnA-3r0rA:undetectable","2ygnA-3r0rA:18.30"],["4FP9_A_SAMA401_1","METHYLTRANSFERASE NSUN4","3r0r","PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN","Porcine circovirus 2",3,"ASP A 122;ARG A  68;ASP A 163","None","0.73A","4fp9A-3r0rA:undetectable","4fp9A-3r0rA:20.16"]]