SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		3 / 3 GLU A 243
LYS A 237
VAL A 239
 None
 1.00A 1l2iA-3r13A:
undetectable		 1l2iA-3r13A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		5 / 12 ILE A 120
VAL A 151
ALA A 227
MET A 197
SER A 210
 None
None
None
None
UNL  A 300 ( 4.1A)
 1.38A 1nbhA-3r13A:
undetectable		 1nbhA-3r13A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		5 / 12 ILE A 120
VAL A 151
ALA A 227
MET A 197
SER A 210
 None
None
None
None
UNL  A 300 ( 4.1A)
 1.37A 1nbhD-3r13A:
2.2		 1nbhD-3r13A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		3 / 3 LYS A 198
ARG A  23
VAL A  22
 None
 1.10A 2r2vC-3r13A:
undetectable
2r2vD-3r13A:
undetectable		 2r2vC-3r13A:
8.95
2r2vD-3r13A:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		5 / 12 ALA A 209
ILE A 223
ILE A 152
SER A 181
ASP A 228
 None
 1.19A 3axtA-3r13A:
2.1		 3axtA-3r13A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		5 / 12 GLY A 183
GLY A 185
THR A 186
ASP A 117
GLY A 211
 UNL  A 300 ( 4.5A)
None
None
UNL  A 300 ( 4.9A)
UNL  A 300 ( 4.1A)
 1.05A 3sglA-3r13A:
undetectable		 3sglA-3r13A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		4 / 7 ILE A  49
LEU A  52
VAL A  71
ALA A  44
 None
 0.82A 4g77A-3r13A:
undetectable		 4g77A-3r13A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		3 / 3 ILE A 153
ILE A 169
MET A 197
 None
 0.70A 5i9yA-3r13A:
undetectable		 5i9yA-3r13A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3r13 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Thermotoga
maritima) 		4 / 7 THR A 160
TRP A 199
HIS A 195
LEU A 125
 None
 1.20A 5x1bA-3r13A:
undetectable
5x1bC-3r13A:
undetectable
5x1bP-3r13A:
undetectable		 5x1bA-3r13A:
17.32
5x1bC-3r13A:
19.93
5x1bP-3r13A:
19.93