SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		6 / 12 VAL A 306
LEU A 270
ILE A 256
GLY A 259
ALA A 261
LEU A 223
 None
 1.32A 1eqhA-3r18A:
undetectable		 1eqhA-3r18A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		6 / 12 VAL A 306
LEU A 270
ILE A 256
GLY A 259
ALA A 261
LEU A 223
 None
 1.30A 1eqhB-3r18A:
undetectable		 1eqhB-3r18A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_B_DVAB8_0
(GRAMICIDIN A)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 5 VAL A 384
TRP A 457
VAL A 428
TRP A 413
 None
 1.38A 1micA-3r18A:
undetectable
1micB-3r18A:
undetectable		 1micA-3r18A:
3.47
1micB-3r18A:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 5 GLU A 169
LEU A 153
LEU A 165
LEU A 167
 None
 0.87A 1np1A-3r18A:
undetectable		 1np1A-3r18A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 0.94A 2ieoA-3r18A:
undetectable		 2ieoA-3r18A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 6 ASP A 156
TYR A 258
PHE A 240
LEU A 219
 None
 0.90A 2w98A-3r18A:
undetectable
2w98B-3r18A:
undetectable		 2w98A-3r18A:
21.01
2w98B-3r18A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 PHE A 136
LEU A 345
GLY A 187
LEU A 202
ALA A 297
 MTE  A 501 (-3.3A)
None
None
None
MTE  A 501 (-3.9A)
 1.13A 3i5uA-3r18A:
undetectable		 3i5uA-3r18A:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 GLY A 242
ARG A 298
ASP A 321
ASP A 246
ASN A 139
 MTE  A 501 ( 3.9A)
None
None
None
None
 1.20A 3jzjA-3r18A:
undetectable		 3jzjA-3r18A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 1.05A 3ndwA-3r18A:
undetectable		 3ndwA-3r18A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 0.98A 3oxxA-3r18A:
undetectable		 3oxxA-3r18A:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 5 ARG A 103
LEU A 107
VAL A 109
ASP A 282
 None
 0.96A 3ufnA-3r18A:
undetectable
3ufnB-3r18A:
undetectable		 3ufnA-3r18A:
12.21
3ufnB-3r18A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 7 VAL A 290
PHE A 136
GLY A 296
PHE A 135
 None
MTE  A 501 (-3.3A)
MTE  A 501 (-3.8A)
MTE  A 501 (-4.7A)
 0.94A 4ejjB-3r18A:
undetectable		 4ejjB-3r18A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 GLY A 374
GLY A 375
ASN A 188
SER A 349
GLY A 207
 None
 1.02A 4fp9D-3r18A:
undetectable		 4fp9D-3r18A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 GLY A 374
GLY A 375
ASN A 188
SER A 349
GLY A 207
 None
 1.03A 4fzvA-3r18A:
undetectable		 4fzvA-3r18A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 5 GLU A 241
SER A 313
ARG A 304
SER A 315
 None
 1.43A 4k17B-3r18A:
undetectable		 4k17B-3r18A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 1.00A 4njuA-3r18A:
undetectable		 4njuA-3r18A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 1.02A 4njuC-3r18A:
undetectable		 4njuC-3r18A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 12 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 0.88A 4njvA-3r18A:
undetectable		 4njvA-3r18A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 11 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 1.02A 4njvB-3r18A:
undetectable		 4njvB-3r18A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 11 ARG A 189
ASP A 321
VAL A 295
GLY A 324
PRO A 346
 None
 0.89A 4njvC-3r18A:
undetectable		 4njvC-3r18A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 5 TYR A 258
GLY A 157
ASP A 156
VAL A 287
 None
 1.15A 4nkvD-3r18A:
undetectable		 4nkvD-3r18A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 8 GLY A 388
GLN A 439
TRP A 392
VAL A 428
 None
 1.04A 5vlmA-3r18A:
undetectable		 5vlmA-3r18A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		4 / 6 GLY A 405
TRP A 408
GLY A 375
GLY A 293
 None
 0.73A 6ag0C-3r18A:
undetectable		 6ag0C-3r18A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		3 / 3 ARG A 195
ARG A 355
ARG A 189
 None
 0.94A 6bplA-3r18A:
undetectable
6bplB-3r18A:
undetectable		 6bplA-3r18A:
10.00
6bplB-3r18A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 3r18 SULFITE OXIDASE
(Gallus
gallus) 		5 / 10 LEU A 124
PRO A 119
LEU A 107
THR A 137
LEU A 183
 None
None
None
MTE  A 501 (-4.2A)
None
 1.41A 6hupD-3r18A:
0.0
6hupE-3r18A:
1.8		 6hupD-3r18A:
10.76
6hupE-3r18A:
10.92