SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r1o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3r1o ODORANT BINDING
PROTEIN, ANTENNAL
(Anopheles
gambiae) 		5 / 10 LEU A 124
VAL A 107
ILE A  57
LEU A  72
PHE A  54
 PLM  A 128 (-4.9A)
PLM  A 128 ( 4.7A)
PLM  A 128 ( 4.5A)
None
PLM  A 128 ( 4.9A)
 1.18A 3fl9F-3r1oA:
undetectable		 3fl9F-3r1oA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3r1o ODORANT BINDING
PROTEIN, ANTENNAL
(Anopheles
gambiae) 		4 / 6 ILE A 118
HIS A  18
ILE A  50
VAL A 107
 None
None
PLM  A 128 ( 4.9A)
PLM  A 128 ( 4.7A)
 0.96A 4zj8A-3r1oA:
undetectable		 4zj8A-3r1oA:
13.81