SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r1w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 3r1w CARBONIC ANHYDRASE
(unidentified) 		3 / 3 VAL A  67
VAL A  94
TRP A  47
 None
 0.73A 1bdwA-3r1wA:
undetectable
1bdwB-3r1wA:
undetectable		 1bdwA-3r1wA:
5.71
1bdwB-3r1wA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3r1w CARBONIC ANHYDRASE
(unidentified) 		5 / 11 ILE A 119
ALA A 123
GLY A 140
GLY A  85
ASN A  82
 None
 1.16A 4jdsC-3r1wA:
undetectable		 4jdsC-3r1wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3r1w CARBONIC ANHYDRASE
(unidentified) 		5 / 12 ILE A 119
ALA A 123
GLY A 140
GLY A  85
ASN A  82
 None
 1.14A 4jlgA-3r1wA:
undetectable		 4jlgA-3r1wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3r1w CARBONIC ANHYDRASE
(unidentified) 		5 / 11 ILE A 119
ALA A 123
GLY A 140
GLY A  85
ASN A  82
 None
 1.15A 5ayfA-3r1wA:
undetectable		 5ayfA-3r1wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3r1w CARBONIC ANHYDRASE
(unidentified) 		4 / 5 LEU A 112
THR A  95
THR A 169
GLY A 171
 None
 1.28A 6gtqA-3r1wA:
undetectable		 6gtqA-3r1wA:
19.80