SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZE2_A_T27A556_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	3r2q	UNCHARACTERIZED GST-LIKE PROTEIN YIBF (Escherichia coli)	5 / 10	PRO A 64 ASN A 152 VAL A 90 PRO A 77 LEU A 18	GSH A 301 (-4.7A) None None None None	1.25A	2ze2A-3r2qA: 0.8	2ze2A-3r2qA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI504_0 (RNA POLYMERASE 3D-POL)	3r2q	UNCHARACTERIZED GST-LIKE PROTEIN YIBF (Escherichia coli)	3 / 3	VAL A 142 GLY A 144 LYS A 147	None	0.79A	4k50I-3r2qA: undetectable	4k50I-3r2qA: 18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UIG_A_EDTA501_0 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	3r2q	UNCHARACTERIZED GST-LIKE PROTEIN YIBF (Escherichia coli)	4 / 6	THR A 150 ASN A 152 ILE A 93 GLU A 94	None	1.34A	5uigA-3r2qA: undetectable	5uigA-3r2qA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1806_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3r2q	UNCHARACTERIZED GST-LIKE PROTEIN YIBF (Escherichia coli)	4 / 6	ILE A 17 LEU A 20 PHE A 26 PHE A 189	None None None EDO A 309 (-3.5A)	0.98A	5vkqB-3r2qA: 3.1 5vkqC-3r2qA: 3.1	5vkqB-3r2qA: 7.48 5vkqC-3r2qA: 7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3r2q	UNCHARACTERIZED GST-LIKE PROTEIN YIBF (Escherichia coli)	4 / 6	ILE A 17 LEU A 20 PHE A 26 PHE A 189	None None None EDO A 309 (-3.5A)	0.95A	5vkqC-3r2qA: 3.1 5vkqD-3r2qA: 3.1	5vkqC-3r2qA: 7.48 5vkqD-3r2qA: 7.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZE2_A_T27A556_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","3r2q","UNCHARACTERIZED GST-LIKE PROTEIN YIBF","Escherichia coli",5,"PRO A  64;ASN A 152;VAL A  90;PRO A  77;LEU A  18","GSH A 301 (-4.7A);None;None;None;None","1.25A","2ze2A-3r2qA:0.8","2ze2A-3r2qA:17.06"],["4K50_I_ACTI504_0","RNA POLYMERASE 3D-POL","3r2q","UNCHARACTERIZED GST-LIKE PROTEIN YIBF","Escherichia coli",3,"VAL A 142;GLY A 144;LYS A 147","None","0.79A","4k50I-3r2qA:undetectable","4k50I-3r2qA:18.04"],["5UIG_A_EDTA501_0","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","3r2q","UNCHARACTERIZED GST-LIKE PROTEIN YIBF","Escherichia coli",4,"THR A 150;ASN A 152;ILE A  93;GLU A  94","None","1.34A","5uigA-3r2qA:undetectable","5uigA-3r2qA:20.23"],["5VKQ_B_PCFB1806_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3r2q","UNCHARACTERIZED GST-LIKE PROTEIN YIBF","Escherichia coli",4,"ILE A  17;LEU A  20;PHE A  26;PHE A 189","None;None;None;EDO A 309 (-3.5A)","0.98A","5vkqB-3r2qA:3.1;5vkqC-3r2qA:3.1","5vkqB-3r2qA:7.48;5vkqC-3r2qA:7.48"],["5VKQ_C_PCFC1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3r2q","UNCHARACTERIZED GST-LIKE PROTEIN YIBF","Escherichia coli",4,"ILE A  17;LEU A  20;PHE A  26;PHE A 189","None;None;None;EDO A 309 (-3.5A)","0.95A","5vkqC-3r2qA:3.1;5vkqD-3r2qA:3.1","5vkqC-3r2qA:7.48;5vkqD-3r2qA:7.48"]]