SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 SER A 461
GLY A 442
LEU A 444
GLY A 419
VAL A 424
 None
 1.23A 1fduC-3r31A:
3.0		 1fduC-3r31A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 432
HIS A 433
VAL A 436
 None
 0.33A 1lqtB-3r31A:
3.1		 1lqtB-3r31A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 432
HIS A 433
VAL A 436
 None
 0.32A 1lquB-3r31A:
2.4		 1lquB-3r31A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 171
VAL A 176
TRP A  68
 None
 0.86A 1nt5A-3r31A:
undetectable		 1nt5A-3r31A:
2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 171
VAL A 176
TRP A  68
 None
 0.86A 1nt5B-3r31A:
undetectable		 1nt5B-3r31A:
2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 9 ALA A 413
ASN A 414
LEU A 439
GLY A 422
GLY A 419
 None
 1.49A 1ru9H-3r31A:
undetectable
1ru9L-3r31A:
undetectable		 1ru9H-3r31A:
17.21
1ru9L-3r31A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 10 ALA A 413
ASN A 414
LEU A 439
GLY A 422
GLY A 419
 None
 1.49A 1ruaH-3r31A:
undetectable
1ruaL-3r31A:
undetectable		 1ruaH-3r31A:
17.21
1ruaL-3r31A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 9 ALA A 413
ASN A 414
LEU A 439
GLY A 422
GLY A 419
 None
 1.49A 1rulH-3r31A:
undetectable
1rulL-3r31A:
undetectable		 1rulH-3r31A:
17.21
1rulL-3r31A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 10 GLY A  77
GLY A 125
ILE A  86
MET A  87
ALA A 203
 None
 1.14A 1x7pA-3r31A:
2.7
1x7pB-3r31A:
undetectable		 1x7pA-3r31A:
20.83
1x7pB-3r31A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 ARG A  88
ASP A 113
ASP A 101
 None
 0.90A 2ejtA-3r31A:
4.8		 2ejtA-3r31A:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 11 ALA A  84
GLY A  77
GLY A 125
ILE A  86
ALA A 203
 None
 0.85A 3dcmX-3r31A:
undetectable		 3dcmX-3r31A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 451
GLY A 422
LEU A 439
ARG A 297
LEU A 282
 None
 1.05A 3ijdB-3r31A:
undetectable		 3ijdB-3r31A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		4 / 8 MET A 319
PRO A 364
VAL A 367
GLY A 361
 None
 1.00A 4mk4A-3r31A:
2.2		 4mk4A-3r31A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		4 / 5 THR A 443
THR A 256
HIS A 477
ASN A 470
 None
 1.03A 4pgfB-3r31A:
2.5		 4pgfB-3r31A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 PRO A  13
ILE A 106
SER A  16
 None
 0.75A 5fsaA-3r31A:
undetectable		 5fsaA-3r31A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		4 / 6 ARG A 314
GLU A 310
GLU A 274
VAL A 277
 None
 1.15A 5h4dA-3r31A:
3.6		 5h4dA-3r31A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3r31 BETAINE ALDEHYDE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 ILE A 127
SER A 116
GLU A 122
PHE A 123
GLY A 125
 None
 1.14A 5l6eA-3r31A:
0.7		 5l6eA-3r31A:
20.20