SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3r3e UNCHARACTERIZED
PROTEIN YQJG
(Escherichia
coli) 		4 / 5 LEU A 182
ASP A 239
ALA A 238
ILE A 223
 None
 0.81A 2qhfA-3r3eA:
undetectable		 2qhfA-3r3eA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3r3e UNCHARACTERIZED
PROTEIN YQJG
(Escherichia
coli) 		3 / 3 LEU A 274
TYR A 278
GLN A 279
 None
 0.73A 2wekA-3r3eA:
undetectable		 2wekA-3r3eA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3r3e UNCHARACTERIZED
PROTEIN YQJG
(Escherichia
coli) 		4 / 7 VAL A 247
ILE A 283
TYR A 278
ILE A 277
 None
 1.04A 3hgxA-3r3eA:
undetectable		 3hgxA-3r3eA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3r3e UNCHARACTERIZED
PROTEIN YQJG
(Escherichia
coli) 		5 / 12 ASP A 239
LEU A 220
LEU A 224
GLY A 225
HIS A 227
 None
 1.37A 3n58C-3r3eA:
undetectable		 3n58C-3r3eA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3r3e UNCHARACTERIZED
PROTEIN YQJG
(Escherichia
coli) 		4 / 6 ILE A 283
ARG A 241
THR A 236
LEU A 235
 None
SO4  A 330 (-3.5A)
None
None
 1.06A 3wg7N-3r3eA:
undetectable
3wg7W-3r3eA:
undetectable		 3wg7N-3r3eA:
21.14
3wg7W-3r3eA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 3r3e UNCHARACTERIZED
PROTEIN YQJG
(Escherichia
coli) 		4 / 8 ILE A 264
ASP A 250
PRO A 251
LEU A 274
 None
 0.88A 4qopC-3r3eA:
undetectable		 4qopC-3r3eA:
22.04