SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 3r3q SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  81
SER A  80
ILE A  69
LEU A 152
VAL A 145
 None
 1.01A 2nnhA-3r3qA:
undetectable		 2nnhA-3r3qA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3r3q SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
(Saccharomyces
cerevisiae) 		4 / 5 PRO A  10
VAL A   9
THR A  68
GLY A  67
 None
 1.21A 3elzB-3r3qA:
1.4		 3elzB-3r3qA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3r3q SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A  96
LEU A  38
LEU A  45
ILE A  98
 None
 1.04A 3u5jA-3r3qA:
undetectable		 3u5jA-3r3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3r3q SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  69
GLY A  67
ASN A  41
PHE A  42
LEU A  45
 None
 1.22A 5fhzA-3r3qA:
undetectable		 5fhzA-3r3qA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3r3q SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  17
PHE A  18
PHE A  32
LEU A  36
 None
None
None
IMD  A 171 (-4.6A)
 1.11A 5x1bP-3r3qA:
undetectable		 5x1bP-3r3qA:
19.09