SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3r3r FERRIPYOCHELIN
BINDING PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 125
SER A 128
VAL A  93
LEU A 105
LEU A 136
LEU A  95
 None
 1.32A 1ya4C-3r3rA:
undetectable		 1ya4C-3r3rA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3r3r FERRIPYOCHELIN
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 SER A 110
GLY A 107
GLY A 144
GLY A 127
ILE A 150
 None
 0.93A 3gczA-3r3rA:
undetectable		 3gczA-3r3rA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3r3r FERRIPYOCHELIN
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A  55
ALA A  56
VAL A 169
GLY A  38
ILE A  39
 None
 0.94A 3ucbB-3r3rA:
undetectable		 3ucbB-3r3rA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 3r3r FERRIPYOCHELIN
BINDING PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A  62
HIS A  91
LYS A  92
 None
 0.97A 4qzuD-3r3rA:
undetectable		 4qzuD-3r3rA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 3r3r FERRIPYOCHELIN
BINDING PROTEIN
(Salmonella
enterica) 		3 / 3 ARG A 158
ARG A 103
ASP A 121
 None
 0.97A 6d8pA-3r3rA:
undetectable		 6d8pA-3r3rA:
12.80