SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
3r45 HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HOLLIDAY JUNCTION
RECOGNITION PROTEIN

(Homo
sapiens;
Homo
sapiens)
4 / 6 SER C  25
ALA C  24
HIS A 104
LEU C  22
None
1.21A 5dzkB-3r45C:
undetectable
5dzkP-3r45C:
undetectable
5dzkB-3r45C:
14.58
5dzkP-3r45C:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
3r45 HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HOLLIDAY JUNCTION
RECOGNITION PROTEIN

(Homo
sapiens;
Homo
sapiens)
4 / 5 SER C  25
ALA C  24
HIS A 104
LEU C  22
None
1.21A 5dzkc-3r45C:
undetectable
5dzkq-3r45C:
undetectable
5dzkc-3r45C:
14.58
5dzkq-3r45C:
10.00